In vitro cytotoxicity of Rhodnius prolixus hemolytic factor and mellitin towards different trypanosomatids

Azambuja, P; Mello, C. B; D'Escoffier, L. N; Garcia, E. S

Azambuja, P; Mello, C. B; D'Escoffier, L. N; Garcia, E. S.

Braz. j. med. biol. res ; 22(5): 597-9, 1989. tab

Article 在 En | LILACS | ID: lil-73899

Responsible library: BR26.1

ABSTRACT

ABSTRACT

Trypanosoma cruzi strain Y and clone Dm28c and other trypanosomatids were exposed to two lytic agents, Rhodnius prolixus hemolytic factor (RHF) and mellitin, in vitro. In both cases, the result was a significant decrease in the number of parasites after a 30-min treatment at 37-C. RHF and mellitin had distinct activities on differente strains and species of trypanosomatids. These observations suggest that RHF may be an important factor in selecting resistant strains of trypanosomes for development in the vector's gut

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索引: LILACS 主要主题: Rhodnius / In Vitro Techniques / Trypanosomatina / Cobra Cardiotoxin Proteins / Melitten 限制: Animals 语言: En 期刊: Braz. j. med. biol. res 期刊主题: BIOLOGIA / MEDICINA 年: 1989 类型: Article / Project document

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