A retrospective study of 18 cases of adenoid cystic cancer at a tertiary care centre in Delhi.
Indian J Cancer
; 2010 Oct-Dec; 47(4): 424-429
Article
在 En
| IMSEAR
| ID: sea-144383
ABSTRACT
Context Adenoid cystic carcinoma (ACC) is a rare neoplasm that usually arises from the salivary, lacrimal, or other exocrine glands. It is characteristically locally infiltrative in nature and has a tendency toward local recurrence, high propensity for perineural invasion, and prolonged clinical course. Aim:
To analyze the presentation and natural history of cases of adenoid cystic tumors of salivary glands in our institution; and to compare with the existing literature. Design andSetting:
Retrospective study at the Department of Radiotherapy. Materials andMethods:
Data on 18 patients of ACC of the salivary glands treated between 2004 and 2008 were reviewed with respect to clinical presentation, stage, and histology.Results:
There were 8 cases of major salivary gland tumors (47%), of which 2 were in the submandibular and 6 were involving the parotid. Ten patients (53%) had minor salivary gland involvement. Two patients had metastasis at the time of presentation. All patients underwent surgery. Radiotherapy was delivered to 16 patients and chemotherapy to 6 patients (concurrent, n = 3 and adjuvant, n = 3) and no adjuvant therapy was given to 2 patients. All patients were alive at a median follow-up of 3 years. No patient developed local or distant failure during the study duration.Conclusion:
ACC has locally aggressive behavior. Radiotherapy adjuvant to surgery improves local control in locally advanced disease. Longer follow-up is mandatory in view of incidence of late metastasis.Key words
全文:
1
索引:
IMSEAR
主要主题:
Radiotherapy
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Aged, 80 and over
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Aged
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Female
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Humans
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Male
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Salivary Gland Neoplasms
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Retrospective Studies
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Treatment Outcome
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Combined Modality Therapy
研究类型:
Observational_studies
限制:
Aged80
国家/地区名称主题:
Asia
语言:
En
期刊:
Indian J Cancer
年:
2010
类型:
Article