ABSTRACT
Background:
Asthma is a chronic inflammatory condition of
lung airways resulting in episodic airflow obstruction.
Aims:
The main objective of this study is tofind the effect of antiasthma medication on
serum IgE levels and
blood eosinophil count.Study
Design:
Thisrandomizedcontrolled trial studywas performed in
children aged 6-15 years of age, with clinically stable and moderate persistent
asthma.
Results:
The findings of this study indicate both group(
Budesonide/
formoterol group and
budesonide group)
patients experienced a significant decrease in
serum IgE levels and
blood eosinophil counts over the study period.However, the difference in two groups was not statistically significant.
Conclusions:
Inhaled
steroids are effective in controlling systemic
inflammation in
asthma as evidenced by a decrease in
IgE levels and
eosinophil counts. However addition of LABA doesn’t have any additive effect.