ABSTRACT
Background and
Objective:
Problem of invasive tests in
breast lesion
diagnosis can be addressed by comparing noninvasive tests with final Histopathological
diagnosis obtained a?er excision
biopsy. Present study was carried out to study diagnos?c u?lity of
mammography, sonography, FNAC compared to excision
biopsy for
diagnosis of
breast lesions
Methods:
Prospec?ve Observa?onal study was carried out among 81
women with
Breast related symptoms.
Digital Mammography Machine, ACUSON S3000TM Ultrasound System; FNAC and
surgery for excision
Biopsy were used. Sensi?vity,
Specificity, Accuracy, Posi?ve and Nega?ve Predic?ve values were measured and p<0.05 was considered as sta?s?cally significant.
Results:
Sonography and FNAC composite have sensi?vity,
specificity, accuracy, posi?ve and nega?ve predic?ve values 100.00%, 81.40%, 90.12%, 82.61% and 100.00% respec?vely.
Mammography+FNAC (97.3%) is not as sensi?ve as Sonography+FNAC (100%), Sonography combined with FNAC is equally sensi?ve to excision
biopsy (100%) and therefore can be used for
screening purpose.
Conclusion:
Contrary to present guidelines which consider
Mammography as most important
screening tool for
Breast Cancer, combina?on of Sonography and FNAC can be considered equally reliable.