ABSTRACT
Aims And Objectives To ?nd the
sensitivity and speci?city of FNAC and Core-Cut
biopsy. To study the ef?cacy of FNAC and Core-Cut
biopsy with that of Histopathological (gross specimen) study in diagnosing a
breast lump. To ?nd limitations of FNAC and Core-Cut
biopsy This is
Hospital based Materials and
Method:
Interventional study at
Tertiary care centre in the department of
General Surgery. All
patients admitted during the period of 24 months with palpable
breast lump coming under the eligibility criteria
will be subjected for FNAC and Core-Cut
biopsy after obtaining informed consents. Data Entry is done by using MS Excel and
Analysis is done by using Suitable Statistical tests.
Results:
Our study of 70
patients, age
incidence was ranged from 18 to 70 years.The age
incidence for the benign lesions ranged from 18 years to 64 years (Mean age 38.5 years, SD= 12.56 years). The
incidence for the malignant lesions ranged from 25 to 70 years (mean age 51.06 years, SD= 10.62 years). Out of total 70
patient, 49
patients had lump in right
breast, 21 had lump in left
breast. Our study True positive for FNAC was 38(54.28%) True negative was 26 (37.14%) and false positive was 0 and false negative were 6 (0.08%), which
lead to the interpretation of
sensitivity of 86 % for FNAC and speci?city of 81.12% for FNAC.Our study True positive for Core-Cut
biopsy was 42(60%) True negative was 26(38%) and False positive was 0(0%) and false negative was 02(2.85%), which
lead to the interpretation of
sensitivity of 95% for Core-Cut
biopsy and speci?city of 92.85 % for Core-cut
biopsy. For Core-Cut
biopsy in our study positive and
negative predictive value was found to be 100% and 59.09% respectively As Both
Sensitivity and Specify of Core-Cut
biopsy is far superior than FNAC, and more number of
Conclusion:
False Negative
reports in FNAC, where we can miss the Malignant
breast Lump, we conclude that, Core-Cut
Biopsy is far superior to FNAC in the diagnostic approach of
breast cancer and, especially in cases of doubt, it is preferable to proceed directly with Core Cut
biopsy.