Automatic measurement of hemoglobin F in blood obtained from patients with hemoglobin E/E and beta-thalassemia/hemoglobin/E.
Southeast Asian J Trop Med Public Health
; 1992 ; 23 Suppl 2(): 91-4
Article
在 En
| IMSEAR
| ID: sea-34706
ABSTRACT
This paper presents an automated determination of hemoglobin (Hb) F in Hb E/E disease using Hi-Auto A1c. Blood specimens collected in Bangkok were frozen, and sent to Japan by air mail for the determination. The automatically determined values showed a high correlation with the values obtained by the classical alkali denaturation method. Hb E/E cases showed 4.24 +/- 1.75% of Hb F. On the other hand, Hb, Hct, MCV and MCH in the disease samples were lower than in the controls, but higher than those of beta-thalassemia/HbE disease. From the results it was concluded that Hb E/E could be differentiated from beta-thalassemia/HbE by combination of Hb F value and MCH or Hb in CBC.
全文:
1
索引:
IMSEAR
主要主题:
Thailand
/
Humans
/
Fetal Hemoglobin
/
Hemoglobin E
/
Hemoglobins
/
Infant, Newborn
/
Reproducibility of Results
/
Chromatography, High Pressure Liquid
/
Beta-Thalassemia
/
Adult
研究类型:
Diagnostic_studies
/
Evaluation_studies
国家/地区名称主题:
Asia
语言:
En
期刊:
Southeast Asian J Trop Med Public Health
年:
1992
类型:
Article