Recent advance in relations of plasticity related gene proteins with nervous system functions and diseases / 中华神经医学杂志

ABSTRACT

Plasticity related gene(PRG) is a subclass of the lipid phosphate phosphatase super family, which is predominantly expressed in the central nervous system in a subtype specific pattern. PRG may be involved in mechanism of nervous system functions and pathogenesis of neuropsychiatric diseases via neuron-specific transcriptional regulation, protein-protein interaction and intracellular signaling pathway regulation. Therefore, this paper reviews the progresses of PRG in recent years and prospects the future research direction.