ABSTRACT
Objective:
Colorectal cancer (CRC) is one of the most common
cancers and the major cause of
cancer death in
China. The aim of this study was to estimate the burden of CRC in
China. Materials and
methods:
Data from the National
Cancer Center (NCC) of
China was used and stratified by area (urban/rural),
sex (
male/
female) for analyzing the age-specific
incidence and
mortality rates.
Time trend of
colorectal cancer was calculated based on the 22 high-quality
cancer registries in
China. National new cases and deaths of
colorectal cancer were estimated using age-specific rates multiplied by the corresponding national
population in 2014. The
Chinese population in 2000 and Segi's
world population were used to calculate age-standardized rates of
colorectal cancer in
China.
Results:
Overall, 370,400 new
colorectal cancer cases and 179,600 deaths were estimated in
China in 2014, with about 214,100 new cases in
men and 156,300 in
women. Meanwhile, 104,000 deaths cases of
colorectal cancer were
men and 75,600 deaths were
women, which accounted for 9.74% and 7.82% of all
cancer incidence and deaths in
China, separately. Relatively higher
incidence and
mortality was observed in
urban areas of
China. And the Eastern areas of
China showed the highest
incidence and
mortality. The age-standardized
incidence and mortality rate of
colorectal cancer has increased by about 1.9% per year for
incidence and about 0.9% per year for mortality rate from 2000 to 2014.
Conclusion:
With gradually higher
incidence and mortality rate in the past 15 years,
colorectal cancer became a major challenge to
China's
public health. Effective control
strategies are needed in
China.