Diagnostic Criteria of Pattern VEP in Adult Monocular Amblyopic Patients

ABSTRACT

PURPOSE: To suggest a diagnostic criteria of pattern visual evoked potential (VEP) in adult monocular amblyopic patients in comparison to normal subjects. METHODS: The medical records of patients' military service certificates from January 2000 to December 2011 were reviewed. The parameters of pattern VEP were analyzed by comparing monocular amblyopic patients with normal controls. RESULTS: This study included 47 monocular amblyopia and 39 normal control patients. All parameters of pattern VEP were statistically significantly different between monocular amblyopic eyes and normal eyes. The cut-off values for diagnosis of adult amblyopia using receiver operating characteristic (ROC) curve were 113.50 msec (P100 latency), 1.05 (ratio of P100 latency), 8.50 msec (interocular difference of P100 latency), and 5.25 microV (interocular difference of P100 amplitude). Cut-off value sensitivities were generally low (51.1%, 70.2%, 53.2%, and 31.9%, respectively). CONCLUSIONS: The value of pattern VEP parameters had limitations due to low sensitivity and could be considered as ancillary diagnostic criteria when diagnosing amblyopia.