A Case of Pyoderma Gangrenosum Associated with Autoimmune Chronic Active Hepatitis / 대한피부과학회지

ABSTRACT

Pyoderma gangrenosum (PG) is an inflammatory ulcerative condition of unclear etiology. In more than 50% of cases, lesions occur in association with an underlying systemic disorder-most notably; inflammatory bowel disease (IBD), rheumatoid arthritis, or a hematologic abnormality. Here, we report a rare case of pyoderma gangrenosum associated with autoimmune chronic active hepatitis. A 34-year-old woman presented with a 2-month history of a painful ulceration on her back. She was clinically diagnosed as having pyoderma gangrenosum and an appropriate exclusion was performed. She had abnormal results for liver biochemical tests, with a hepatitis-like picture and high titer of antinuclear antibodies. According to the scoring system proposed by the International Autoimmune Hepatitis Group she had `definite' autoimmune hepatitis and responded well to immunesuppressive treatment.