Risk Factors Associated with Respiratory Virus Detection in Infants Younger than 90 Days of Age / 소아감염
Korean Journal of Pediatric Infectious Diseases
; : 22-28, 2014.
Article
在 Ko
| WPRIM
| ID: wpr-185155
Responsible library:
WPRO
ABSTRACT
PURPOSE:
This study aimed at determining the detection rate of respiratory viruses and at investigating the risk factors associated with respiratory virus detection in young infants.METHODS:
From September 2011 to August 2012, nasopharyngeal swabs were obtained from 227 infants aged < or =90 days with suspected infectious diseases, including sepsis. We performed a retrospective analysis of their clinical characteristics. The prevalence of respiratory viruses in their nasopharyngeal swabs was assayed by real-time polymerase chain reaction (real-time PCR).RESULTS:
In total, 157 (69.2%) infants had more than one of the following respiratory viruses respiratory syncytial virus (n=75), rhinovirus (n=42), influenza virus (n=18), parainfluenza virus (n=15), human metapneumovirus (n=9), coronavirus (n=9), adenovirus (n=4), and bocavirus (n=3). During the same period, bacterial infections were confirmed in 24 infants (10.6%). The detection of respiratory viruses was significantly associated with the presence of cough, a family history of respiratory illness, and a seasonal preference (fall/winter). Using logistic regression analysis, these 3 variables were also identified as significant risk factors. During fall and winter, detection of respiratory viruses was significantly higher in infants who did not have a bacterial infection.CONCLUSION:
Respiratory virus is an important pathogen in young infants admitted to a hospital, who are suspected with infectious diseases. Detection of respiratory viruses in young infants was associated with seasonality (fall/winter), presence of respiratory symptoms and a family history of respiratory illness.Key words
全文:
1
索引:
WPRIM
主要主题:
Orthomyxoviridae
/
Respiratory Syncytial Viruses
/
Respiratory Tract Infections
/
Rhinovirus
/
Seasons
/
Bacterial Infections
/
Virus Diseases
/
Logistic Models
/
Adenoviridae
/
Nasopharynx
研究类型:
Diagnostic_studies
/
Etiology_studies
/
Observational_studies
/
Prevalence_studies
/
Prognostic_studies
限制:
Humans
/
Infant
语言:
Ko
期刊:
Korean Journal of Pediatric Infectious Diseases
年:
2014
类型:
Article