An Autopsy Case of Pick's Disease
Journal of the Korean Neurological Association
; : 786-789, 2000.
Article
在 Ko
| WPRIM
| ID: wpr-193153
Responsible library:
WPRO
ABSTRACT
Pick's disease is a rare neurodegenerative disorder presenting cortical type of dementia. Pick's disease shows unique clinical and pathological features, that are due to a degeneration of fronto-temporal lobes of the cerebrum. The authors experienced a case of Pick's disease in a 58-year-old male patient who had dementia symptoms for five years. The patient showed compulsive behavior since five years ago. Memory decline started from four years ago and progressed. Brain CT disclosed lobar atrophy of the cerebral gyri in frontal and temporal lobes. He died of septicemia associated with aspiration pneumonia. At autopsy, both cerebral hemispheres showed marked encephalomalacia. The gyral atrophy was moderately severe in prefrontal and anterior temporal lobes. Coronal section disclosed moderate dilatation of the lateral ventricles. Microscopically, there were marked neuronal loss in prefrontal and anterior temporal cortices. Also noted were Pick's cells and Pick's body in occasional pyramidal cells preserved.
Key words
全文:
1
索引:
WPRIM
主要主题:
Pneumonia, Aspiration
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Atrophy
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Autopsy
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Temporal Lobe
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Brain
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Pyramidal Cells
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Sepsis
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Compulsive Behavior
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Neurodegenerative Diseases
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Lateral Ventricles
限制:
Humans
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Male
语言:
Ko
期刊:
Journal of the Korean Neurological Association
年:
2000
类型:
Article