Usefulness of Hyperemic Microvascular Resistance Index as a Predictor of Clinical Outcomes in Patients with ST-Segment Elevation Myocardial Infarction
Korean Circulation Journal
; : 194-201, 2015.
Article
在 En
| WPRIM
| ID: wpr-19608
Responsible library:
WPRO
ABSTRACT
BACKGROUND AND OBJECTIVES:
Microvascular function is a useful predictor of left ventricular functional changes in patients with ST-segment elevation myocardial infarction (STEMI). We evaluated the usefulness of the hyperemic microvascular resistance index (hMVRI) for predicting long-term major adverse cardiovascular events (MACEs) in patients with STEMI assessed immediately after primary percutaneous coronary intervention (PCI). SUBJECTS ANDMETHODS:
hMVRI were evaluated in 145 patients with first acute STEMI treated with primary PCI using an intracoronary Doppler wire. hMVRI was defined as the ratio of mean aortic pressure over hyperemic averaged peak velocity of infarct-related artery. Major adverse cardiovascular events (MACEs) included cardiac death and re-hospitalization for congestive heart failure.RESULTS:
During the mean follow-up of 85+/-43 months, MACEs occurred in 17.2% of patients. Using a receiver-operating characteristics analysis, hMVRI >2.82 mm Hg.cm-1.sec (sensitivity 87%; specificity 69%; and area under curve 0.818) was the best cut-off values for predicting future cardiac events. The Cox proportional hazard analysis showed that hMVRI was an independent predictor for long-term MACEs (hazard ratio 1.741, 95% confidence interval 1.348-2.264, p2.82 mm Hg.cm-1.sec (p<0.001).CONCLUSION:
hMVRI was a strong predictor of long-term MACEs in patients with STEMI treated with primary PCI.Key words
全文:
1
索引:
WPRIM
主要主题:
Arteries
/
Incidence
/
Follow-Up Studies
/
Sensitivity and Specificity
/
Area Under Curve
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Death
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Percutaneous Coronary Intervention
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Arterial Pressure
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Heart Failure
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Microcirculation
研究类型:
Diagnostic_studies
/
Incidence_studies
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Observational_studies
/
Prognostic_studies
限制:
Humans
语言:
En
期刊:
Korean Circulation Journal
年:
2015
类型:
Article