Recent Advances in Palliative Chemotherapy for Unresectable Pancreatic Cancer / 대한소화기학회지
The Korean Journal of Gastroenterology
; : 150-153, 2015.
Article
在 Ko
| WPRIM
| ID: wpr-202462
Responsible library:
WPRO
ABSTRACT
Pancreatic adenocarcinoma is one of the fatalist malignancies. A large proportion of patients are diagnosed with unresectable stage pancreatic cancer at the time of presentation. Gemcitabine is a standard chemotherapeutic agent since 1997, but survival benefit is not satisfactory. Recent clinical study proved that several new combination chemotherapy regimens are superior to gemcitabine single chemotherapy and extended overall survival. However, its prognosis still remains grim. Current research is taking a multidirectional approach in the hope of developing more effective treatments. This article reviews the major clinical trial data that is the basis for the current chemotherapy regimens used as first- and second-line treatments for advanced pancreatic adenocarcinoma. This article also reviews the current ongoing clinical trials, which include the use of molecular targeting agents and immune therapies.
Key words
全文:
1
索引:
WPRIM
主要主题:
Pancreatic Neoplasms
/
Adenocarcinoma
/
Antineoplastic Combined Chemotherapy Protocols
/
Deoxycytidine
/
Protein Kinase Inhibitors
/
Immunotherapy
/
Antimetabolites, Antineoplastic
/
Antineoplastic Agents
限制:
Humans
语言:
Ko
期刊:
The Korean Journal of Gastroenterology
年:
2015
类型:
Article