A Case of Secondary Renal Amyloidosis in Children with Juvenile Rheumatoid Arthritis
Journal of the Korean Society of Pediatric Nephrology
; : 243-250, 2002.
Article
在 Ko
| WPRIM
| ID: wpr-216053
Responsible library:
WPRO
ABSTRACT
Amyloidosis comprises a diverse group of systemic and local diseases characterized by organ involvement by the extracellular deposition of fibrils composed of subunits of a variety of normal serum proteins. Secondary amyloidosis is caused by the deposition of amyloid A(AA) protein in chronic inflammatory disease. Juvenile rheumatoid arthritis(JRA) has been known to be the most common cause of secondary amyloidosis. We experienced one case of secondary renal amyloidosis in a 12-year-old girl who had suffered from JRA for several years who had visited our renal clinic to evaluate the proteinuria with microscopic hematuria which was detected by chance at school urine screening examination. Apple green birefringence was observed under polarized light with Congo red stain and characteristic electron microscopic findings was also noted in renal tissues which was obtained by percutaneous renal biopsy. In our knowledge, this is the first case report of secondary renal amyloidosis developed in pediatric age in Korea.
Key words
全文:
1
索引:
WPRIM
主要主题:
Arthritis, Juvenile
/
Proteinuria
/
Biopsy
/
Birefringence
/
Blood Proteins
/
Mass Screening
/
Congo Red
/
Hematuria
/
Amyloid
/
Amyloidosis
研究类型:
Prognostic_studies
/
Screening_studies
限制:
Child
/
Female
/
Humans
国家/地区名称主题:
Asia
语言:
Ko
期刊:
Journal of the Korean Society of Pediatric Nephrology
年:
2002
类型:
Article