Studies on chemical constituents of phenols in fresh Houttuynia cordata / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the aqueous constituents of Houttuynia cordata.</p><p><b>METHOD</b>Various columns including Diaion HP-20, Sephadex LH-20, ODS and silica gel were employed for the isolation and purification of compounds from H. cordata. The structures of the compounds were identified by physiochemical properties and spectral analysis.</p><p><b>RESULT</b>Five compounds were isolated, and their structures were identified as chlorogenic methyl ester (1), (E)-4-Hydroxy-4-[3'-(beta-D-glucopyranosyloxy) butylidene]-3, 5, 5-trimethyl-2-cyclohexen-1-one (2), 2-(3, 4-dihydroxyphenyl) ethyl-beta-D-glucopyranoside (3), p-hydroxyphenethyl-beta-D-glucoside (4), 4-(beta-D-glucopyranosyloxy)-3-hydroxy-Benzoic acid (5).</p><p><b>CONCLUSION</b>All compounds were isolated from this plant for the first time.</p>