Comparative study on the ability of adhesion and invasion of different fimA genetypes of Porphyromonas gingivalis to oral epithelial cells / 中华口腔医学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To compare the ability of adhesion and invasion to epithelial cells by Porphyromonas gingivalis (Pg) strains with different fimA separated from Chinese.</p><p><b>METHODS</b>Cultured method and antibiotic protection method were used to determine the adhesive and invasive ability of Pg with different fimA genetypes. The adhesion was observed by scanning electron microscope.</p><p><b>RESULTS</b>All the strains adhered and invaded to KB cells, and the adhesion rate ranged from 0.523% to 37.125% and invasive rate from 0.017% to 3.750%.The adhesive and invasive ability among different fimA genotypes showed no significant difference (P > 0.05).</p><p><b>CONCLUSIONS</b>There is no significant correlation between fimA genotype and ability in adhesion and invasion to KB cells.</p>