Relationship between chronic hepatitis C and type II diabetes mellitus / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
; (6): 46-49, 2003.
Article
在 Zh
| WPRIM
| ID: wpr-281857
Responsible library:
WPRO
ABSTRACT
<p><b>BACKGROUND</b>To study the relationship between HCV infection and the development of type II diabetes mellitus.</p><p><b>METHODS</b>1. The case record files of 126 patients with chronic hepatitis C vs. 227 with chronic hepatitis B were reviewed and the laboratory and demographic data were extracted. 2. Anti-HCV and HBsAg were determined for 160 type II diabetes patients and 223 healthy adults by ELISA.</p><p><b>RESULTS</b>1. The occurrence of diabetes in patients with chronic hepatitis C was 19.05%, higher than 8.37% in patients with chronic hepatitis B (P<0.01). Age and HCV infection were independent risk factors for diabetes. 2. Five patients with type II diabetes were anti-HCV positive (3.12%) while none of the 223 healthy adults was anti-HCV positive (P<0.05). Seven patients with diabetes (4.37%) and 12 healthy adults (5.38%)were HBsAg positive (P>0.05).</p><p><b>CONCLUSIONS</b>1. The occurrence of diabetes was significantly higher in patients with HCV related liver disease than in patients with HBV related liver disease. 2. The occurrence of anti HCV was higher in diabetes patients than in healthy adults. HCV may play a role in the development of diabetes mellitus.</p>
全文:
1
索引:
WPRIM
主要主题:
Virology
/
Random Allocation
/
Comorbidity
/
China
/
Epidemiology
/
Prevalence
/
Risk Factors
/
Risk Assessment
/
Hepatitis B, Chronic
/
Hepatitis C, Chronic
研究类型:
Clinical_trials
/
Etiology_studies
/
Prevalence_studies
/
Risk_factors_studies
限制:
Adult
/
Female
/
Humans
/
Male
国家/地区名称主题:
Asia
语言:
Zh
期刊:
Chinese Journal of Experimental and Clinical Virology
年:
2003
类型:
Article