Long-term efficacy of sirolimus-eluting stents (Cypher) versus bare metal stents for patients with ST-segment elevation myocardial infarction / 中华心血管病杂志
Chinese Journal of Cardiology
; (12): 108-112, 2008.
Article
在 Zh
| WPRIM
| ID: wpr-299489
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To observe the safety and long-term efficacy of Cypher stent versus bare metal stents (BMS) in patients with STEMI.</p><p><b>METHODS</b>From Dec 2002 to Mar 2005, clinical and angiographic data of 407 consecutive patients with STEMI treated with Cypher stent (n = 131) or BMS (n = 276) were analyzed and followed up for a mean period of 28.7 +/- 11.7 months. Major adverse cardiac events (MACE): death, nonfatal reinfarction and target lesion revascularization (TLR) during follow up was compared between two groups.</p><p><b>RESULTS</b>Compared with the BMS group, diameter of vessels were significantly smaller (3.0mm vs. 3.2mm, P = 0.00), the incidence of MACE (6.1% vs. 12.7%, P = 0.04) and total mortality (1.5% vs. 6.9%, P = 0.02) were significantly lower in the Cypher group. The relative risk for MACE in Cypher group was 0.61 (P < 0.05), while there was no significant difference in the rate of stent thrombosis, rate of target lesion revascularization and restenosis.</p><p><b>CONCLUSION</b>Utilization of Cypher in the setting of primary PCI for STEMI was safe and improved the long-term clinical outcomes compared to BMS.</p>
全文:
1
索引:
WPRIM
主要主题:
Therapeutics
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Angioplasty, Balloon, Coronary
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Stents
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Follow-Up Studies
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Treatment Outcome
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Sirolimus
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Drug-Eluting Stents
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Methods
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Myocardial Infarction
研究类型:
Etiology_studies
/
Observational_studies
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Prognostic_studies
限制:
Adult
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Aged
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Aged80
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Female
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Humans
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Male
语言:
Zh
期刊:
Chinese Journal of Cardiology
年:
2008
类型:
Article