Comparison of two different methods to detect HIV antibodies / 中华实验和临床病毒学杂志
Chinese Journal of Experimental and Clinical Virology
; (6): 492-493, 2012.
Article
在 Zh
| WPRIM
| ID: wpr-304999
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>Evaluated the chemiluminescence and enzyme-linked immunosorbent assay (ELISA) to detect HIV antibodies, and compared the results, to provide a reference for the selection and clinical application of HIV screening.</p><p><b>METHODS</b>3000 cases of our hospital patients were measured by enzyme-linked immunosorbent assay and chemiluminescence immunoassay, using comfirmming experimental results as gold standards. Comparing sensitivity, specificity and other Indicators.</p><p><b>RESULTS</b>In the diagnosis of HIV infection, enzyme-linked immunosorbent assay and chemiluminescence immunoassay had no significant difference. The positive rate of enzyme-linked immunosorbent assay was 0.93%, while the sensitivity and specificity were 89.66%, 99.93%, the positive rate of chemiluminescence immunoassay was 1.03%, while the sensitivity and specificity were 100%, 99.93%, respectively.</p><p><b>CONCLUSION</b>Both methods are suitable for screening of HIV, having high specificity, and chemiluminescence has greater sensitivity than ELISA.</p>
全文:
1
索引:
WPRIM
主要主题:
Blood
/
Enzyme-Linked Immunosorbent Assay
/
HIV Antibodies
/
HIV Infections
/
Sensitivity and Specificity
/
Diagnosis
/
Allergy and Immunology
/
Luminescent Measurements
/
Methods
研究类型:
Diagnostic_studies
/
Guideline
限制:
Adolescent
/
Adult
/
Aged
/
Female
/
Humans
/
Male
语言:
Zh
期刊:
Chinese Journal of Experimental and Clinical Virology
年:
2012
类型:
Article