Primary malignant tumor of the appendix: clinicopathological analysis of 22 cases / 浙江大学学报·医学版

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the clinicopathological and immunohistochemical features of primary malignant tumor of the appendix.</p><p><b>METHODS</b>The clinical data were reviewed; and histopathological and immunohistochemical features were analyzed in 22 cases with primary malignant tumor of the appendix.</p><p><b>RESULT</b>In 22 cases of primary malignant tumor of the appendix, 19 cases were carcinoid and 3 were adenocarcinoma. Immunohistochemistry showed that the carcinoid was positively reacted to the neuroendocrine markers, and the adenocarcinoma was negatively reacted to the neuroendocrine markers.</p><p><b>CONCLUSION</b>Immunohistochemistry is useful in diagnosis of primary malignant tumor of the appendix, a rare type of cancer.</p>