Alkaloids from roots and stems of Litsea cubeba / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 3964-3968, 2014.
Article
在 Zh
| WPRIM
| ID: wpr-310957
Responsible library:
WPRO
ABSTRACT
A phytochemical investigation on the roots and stems of Litsea cubeba led to the isolation of seven isoquinolone alkaloids. By spectroscopic analysis and comparison of their 1H and 13C-NMR data with those in literatures, these alkaloids were identified as (+)-norboldine (1), (+)-boldine (2), (+)-reticuline (3), (+)-laurotetanine (4), (+)-isoboldine (5), (+)-N-methyl-laurotetanine (6), and berberine (7), respectively. Among them, 7 was isolated from the genus for the first time. The evaluation of these compounds showed weak anti-inflammatory activity against NO production in RAW 267.4 and BV-2 cells.