Comparison of primary extraovarian peritoneal serous papillary carcinoma with stage III-IV ovarian papillary serous carcinoma / 中华肿瘤杂志
Chinese Journal of Oncology
; (12): 171-173, 2005.
Article
在 Zh
| WPRIM
| ID: wpr-331199
Responsible library:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>Extraovarian peritoneal serous papillary carcinoma (EPSPC) is both histologically and clinically similar to stage III-IV ovarian papillary serous carcinoma (OPSC). The purpose of this study is to investigate the clinical findings, treatment, and outcome of EPSPC patients compared with stage III-IV OPSC patients.</p><p><b>METHODS</b>The data of 12 EPSPC patients and 45 stage III-IV OPSC patients were retrospectively reviewed, comparing the characteristics on clinical presentation and treatment, sensitivity to first-line chemotherapy agents and survival.</p><p><b>RESULTS</b>By analysis of patients' characteristics, presenting signs and symptoms, type and extent of surgery, tumor response to first-line chemotherapy, recurrence-free interval, recurrence site and serum CA-125 levels, no significant difference was observed between the EPSPC patients and stage III-IV OPSC controls. The prevailing presenting symptoms were abdominal mass and ascites. The mainstay of treatment was debulking surgery followed by adjuvant platinum-based chemotherapy. The complete clinical response of stage III-IV OPSC was 91.8% compared with 25.0% for women with EPSPC (P < 0.01).</p><p><b>CONCLUSION</b>The clinical and surgical characteristics of EPSPC are similar to those of stage III-IV OPSC. When the same treatment strategy is applied, similar response and survival are expected in either condition.</p>
全文:
1
索引:
WPRIM
主要主题:
Ovarian Neoplasms
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Pathology
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Peritoneal Neoplasms
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General Surgery
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Blood
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Antineoplastic Combined Chemotherapy Protocols
/
Doxorubicin
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Retrospective Studies
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Follow-Up Studies
/
Cisplatin
研究类型:
Observational_studies
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Prognostic_studies
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Risk_factors_studies
限制:
Aged
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Female
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Humans
语言:
Zh
期刊:
Chinese Journal of Oncology
年:
2005
类型:
Article