Advance in studies on effect of paeoniflorin on nervous system / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 297-301, 2013.
Article
在 Zh
| WPRIM
| ID: wpr-346829
Responsible library:
WPRO
ABSTRACT
Paeoniflorin (PF) is the chief active component of paeonia, with diverse pharmacological actions and wide application. Recently, the effect of PF on nervous system has attracted increasingly more attention. According to current study findings, PF can ameliorate the decline of memory and learning capacities in many dementia model animals, and have effect in protecting the cerebral ischemia injury, treating Parkinson's disease, reliving pain and improving neural synapse plasticity. Thought its mechanism has not been clarified, current findings show that adenosine A1 receptor plays an important role, while M cholinergic receptor, opiate receptor, calcium ion channel and NF-KB may also play a part in paeoniflorin's effect on nervous system.
全文:
1
索引:
WPRIM
主要主题:
Pharmacology
/
Benzoates
/
Bridged-Ring Compounds
/
Calcium Channels
/
NF-kappa B
/
Monoterpenes
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Receptor, Adenosine A1
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Glucosides
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Learning
/
Memory
研究类型:
Prognostic_studies
限制:
Animals
语言:
Zh
期刊:
China Journal of Chinese Materia Medica
年:
2013
类型:
Article