The role of Toll-like receptor 4 in malignant lymphoma / 实用肿瘤学杂志
Practical Oncology Journal
; (6): 456-459, 2014.
Article
在 Zh
| WPRIM
| ID: wpr-499212
Responsible library:
WPRO
ABSTRACT
The pathogenesis of malignant lymphoma has been an important topic in tumor research ,but it is still unclear.Recent clinical studies showed that the expression level of Toll -like receptor 4(TLR4)was signif-icantly high in mantle cell lymphoma tissue and a variety of lymphoma cell lines .At the same time,the TLR4 ex-pression level was correlated with prognosis .The Role of TLR4 in malignant lymphoma for occurrence and devel-opment is reviewed in this article ,which may elucidate the pathogenesis and provide a new basis for the therapy of lymphoma.