PDTC suppresses cholesterol induced C-reactive protein expression in L-02 cell line / 西安交通大学学报(医学版)
Article
在 Zh
| WPRIM
| ID: wpr-546172
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WPRO
ABSTRACT
Objective To study the effects of PDTC on cholesterol induced C-reactive protein gene expression in L-02 cell line.Methods Human hepatocyte cell line L-02 was cultured in vitro;growth-arrested cells were divided into 3 groups,cholesterol group,PDTC+cholesterol group and control group.After 48 h incubation,western blot and immunoturbidimetry assays were carried out to detect intracellular and secreted C reactive protein expression.Results Cholesterol stimulated CRP gene expression in L-02(P