Risk Factors for Metachronous Recurrence after Endoscopic Submucosal Dissection of Early Gastric Cancer
Journal of Korean Medical Science
; : 421-426, 2017.
Article
在 En
| WPRIM
| ID: wpr-56123
Responsible library:
WPRO
ABSTRACT
Although endoscopic submucosal dissection (ESD) is widely accepted as a curative treatment method for early gastric cancer (EGC) worldwide, metachronous recurrence often occurs after ESD for EGC. However, there are insufficient data about the role of Helicobacter pylori (H. pylori) infection and other risk factors for recurrence. We aimed to compare the metachronous lesion in the H. pylori persistent group and the eradicated group, and to identify risk factors for metachronous lesion. We retrospectively analyzed 782 patients who underwent ESD between January 2008 and December 2013. We excluded patients with dysplasia or patients who were not tested for H. pylori infection. One hundred eighty-five patients were enrolled. We studied risk factors for recurrence, and used survival analysis to test. There were 24 patients with metachronous recurrence after ESD for EGC among the group. The incidence of metachronous gastric lesions after ESD for EGC developed more in the over 70-year-old group (P = 0.025) and more in the H. pylori persistent group (P = 0.008). In conclusion, H. pylori infection and old age are independent risk factors for metachronous gastric lesions after ESD in EGC.
Key words
全文:
1
索引:
WPRIM
主要主题:
Recurrence
/
Stomach Neoplasms
/
Incidence
/
Retrospective Studies
/
Risk Factors
/
Helicobacter pylori
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Methods
研究类型:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
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Risk_factors_studies
限制:
Aged
/
Humans
语言:
En
期刊:
Journal of Korean Medical Science
年:
2017
类型:
Article