The clinical observation and analysis of domperidone oral liquid combined with multienzyme tablets for the treatment of pediatric functional dyspepsia / 中国基层医药

ABSTRACT

Objective To explore the effect of domperidone oral liquid combined with multienzyme tablets for the treatment of functional dyspepsia.Methods 150 children with functional dyspepsia were selected,they were randomly divided into the observation group and control group by using the random number table method,with 75 ca-ses each group.The control group received domperidone oral liquid treatment and the observation group were given domperidone oral liquid combined with multienzyme tablets treatment.The main clinical symptom score and improve-ment time of two groups,and assess the adverse reactions were observed.Results The satiety,loss of appetite, abdominal discomfort,nausea and vomiting and fecal condition score of the observation group after treatment were (0.48 ±0.13),(0.53 ±0.22),(0.21 ±0.18),(0.79 ±0.38),(0.28 ±0.19),which were lower than the control group after treatment (t =8.46,9.27,7.94,10.11,8.04,all P 0.05).Conclusion There was better effect on domperidone oral liquid combined with multienzyme tablets on func-tional dyspepsia in children,which could improve the patient's clinical symptoms or signs significantly.And could in-duce the improvement time.