ABSTRACT
Objective:
To investigate the effect of
enteral nutrition support by CT-guided percutaneous gastrostomyon the
nutritional status of
patients with
esophageal cancer complicated with
dysphagia during
radiotherapy.
Methods:
Therewere46 cases of
esophageal cancer patients with
dysphagia treated with CT-guided percutaneousgastrostomy.Others 43 cases of
esophageal cancer by oral
feeding in
patients with
dysphagia as control groupduringthe sametimein our
hospital radiotherapy center.
Patients in the
observation group were ingested daily through the
gastrostomy,and the
nutritional intake of the
control group included oral
ingestion and
intravenous infusion.All
patients were measuredthe
body height,
body weight (BW).
body mass index (BMI),
Serum levels of
serum albumin (ALB),pre-
albumin (PA) and
hemoglobin (HB) before and after
radiotherapy.We also observed the
incidence of acute
radiation esophagitis and the completion of the
treatment plan during
radiotherapy in both groups,and to observe the two groups of
patients the
incidence rate of
radiotherapy and
treatment plan during the completion of acute
radiation esophagitis.
Results:
There was no significant difference in BW,BMI,ALB,PA,HB before
radiotherapy between the two groups (t =0.84,0.63,-1.07,-0.81,1.48,P > 0.05).The BW,BMI,ALB,PA and HB of the
observation group were significantly higher than those of the
control group at the end of
radiotherapy,which werestatistically significant (t=3.30,4.65,6.82,43.56,31.91,P < 0.01).During the
radiotherapy,the total
incidence of acute
radiation esophagitis in the
observation group was significantly lower than that in the
control group,(x2=3.971,P< 0.05).In addition,the completion rate of the observationgroup was significantly higher than that of the
control group (x2 =6.811,P < 0.01).
Conclusion:
To the
Patients with
dysphagia of
esophageal cancer,
enteral nutrition byCT guided percutaneous
gastrostomy,can improve the
malnutrition,the immune function of the
patients and reduce the acute
radiation esophagitis during
radiotherapy and ensure the successful completion of the
treatment plan.