Application of lipid - regulating drugs in prevention and treatment of nonalcoholic fatty liver disease / 临床肝胆病杂志

ABSTRACT

Nonalcoholic fatty liver disease (NAFLD)is a clinicopathological syndrome characterized by diffuse macrovesicular steatosis in hepatocytes and is caused by the factors except excessive drinking and other specific factors for liver injury. In particular,lipid metabolism disorder is a significant characteristic of NAFLD,and improvement of dyslipidemia is an important method for the prevention and treatment of NAFLD. Lipid - regulating drugs can not only reduce blood lipids,but also promote the transportation of lipids to the liver for metabolism, which may cause liver lipid accumulation and aggravate liver injury. At present,there are still controversies over the application of lipid -regulating drugs in the treatment of NAFLD in China. Rational use of lipid - regulating drugs has become an important topic in the prevention and treatment of NAFLD. This article summarizes the application of lipid - regulating drugs in NAFLD,in order to provide a reference for lipid - regulating drugs in the prevention and treatment of NAFLD.