Analysis of the correlation on serum sex hormones levels,neural transmitter and the patients with postpartum depression / 实用医学杂志

ABSTRACT

Objective To explore the correlation on serum sex hormones levels,neural transmitter and the patients with postpartum depression.Methods 80 cases of patients with postpartum depression were the obser-vation group,80 cases of maternal health were the control group.The scores of EPDS,HAMD,HAMA,the levels of E2,PRL,P,5-HT,DA,NE,OFQ were compared.Results The scores of EPDS,HAMD,HAMA for the ob-servation group were higher than the control group(P<0.05).There had significant difference on the levels of E2, PRL,P(P < 0.05). There had significant difference on the levels of 5-HT,DA,NE,OFQ on postpartum 2 d, 1 week for the two groups(P<0.05).It had positive correlation on EPDS,scors,PRL,P,OFQ(r=0.496,r=0.417,r=0.505,P<0.05).It had negative correlation on EPDS,E2,5-HT,DA,NE(r=-0.597,r=-0.583, r =-0.517,r =-0.422,P < 0.05). Conclusions It significantly related on serum sex hormones levels,neural transmitter and the patients with postpartum depression,and it can predict and prevent postpartum depression by early detection the levels of serum sex hormones levels,neural transmitter.