Is Antipsychotic Intake a Risk Factor for the Restless Legs Syndrome?
Journal of the Korean Neurological Association
; : 49-53, 2009.
Article
在 Ko
| WPRIM
| ID: wpr-70320
Responsible library:
WPRO
ABSTRACT
BACKGROUND:
Restless-legs syndrome (RLS) is known to be caused by dopaminergic hypofunction in the brain. We investigated whether antipsychotics that act as antidopaminergics increase the risk of RLS.METHODS:
We prospectively recruited 72 schizophrenic patients who had been medicated with antipsychotic drugs in a psychiatry clinic. We evaluated RLS diagnostic criteria and basic sleep habits using the Epworth Sleepiness Scale and Pittsburgh Sleep Quality Index by face-to-face interviews using a structured questionnaire. We also applied the Unified Parkinson's Disease Rating Scale to evaluate extrapyramidal symptoms.RESULTS:
Three of the 72 patients (4.2%) met RLS criteria, which is similar to the previously reported RLS incidence among the general population in Korea.CONCLUSIONS:
There is no evidence that antipsychotics increase the risk of RLS. We believe that the mild antidopaminergic effect of antipsychotics does not overwhelm their prominent antipsychotic effect.Key words
全文:
1
索引:
WPRIM
主要主题:
Parkinson Disease
/
Restless Legs Syndrome
/
Schizophrenia
/
Antipsychotic Agents
/
Brain
/
Incidence
/
Prospective Studies
/
Surveys and Questionnaires
/
Risk Factors
研究类型:
Etiology_studies
/
Incidence_studies
/
Observational_studies
/
Prognostic_studies
/
Qualitative_research
/
Risk_factors_studies
限制:
Humans
语言:
Ko
期刊:
Journal of the Korean Neurological Association
年:
2009
类型:
Article