Progress in identifying genetic susceptibility genes for familial breast cancer / 中国肿瘤临床
Chinese Journal of Clinical Oncology
; (24): 1113-1116, 2018.
Article
在 Zh
| WPRIM
| ID: wpr-706893
Responsible library:
WPRO
ABSTRACT
Breast cancer is the most common malignant tumor in women. With the development of cell biology and molecular bio-technology, great progress has been made in the study of the pathogenesis of breast cancer. Familial breast cancer is closely related to the mutation of susceptible genes. Selected susceptible genes of breast cancer can be grouped into three categories: high-, medium-, and low-penetrance susceptible genes. The means of identifying the high-risk sites of pathogenic mutation and genetic polymorphism is the focus of research on the genetic predisposition of breast cancer.