Cell Based Treatment for Middle Age Patients with Osteoarthritis

ABSTRACT

While many treatments have been performed to repair the chondral defects during last two decades, most of the repaired tissue has shown fibrocartilage or hyaline-like cartilage. Therefore, the clinical outcomes of conventional treatments are unrealiable and unpredictable. Cell-based treatments have recently emerged to regenerate the cartilage with better biomechanical properties and histological quality so that it resembles nature hyaline cartilage. This review discusses the current methodology of the cell-based treatments and their clinical outcomes.