ABSTRACT
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AIM:
To observe the clinical value of Yiqihuoxuehuayu decoction combined with
triamcinolone acetonide and 532nm
argon laser in the
treatment of
macular edema(ME)
secondary to
branch retinal vein occlusion(BRVO).<p>
METHODS:
Totally 80
patients(80
eyes)with ME
secondary to BRVO admitted to the
hospital from January 2014 to August 2016 were randomly divided into
control group and
observation group, with 40 cases(40
eyes)in each group.
Control group was given
intravitreal injection of
triamcinolone acetonide combined with 532nm
argon laser photocoagulation, and
observation group was additionally given Yiqihuoxuehuayu decoction. The best corrected
visual acuity(BCVA), central foveal thickness(CMT)and
intraocular pressure were measured before
treatment and at 1wk, 1mo and 3mo of
treatment. The
visual acuity, improvement effects of ME and improvements of symptoms(
metamorphopsia,
hemorrhage, exudation, <i>etc.</i>)were compared between the two groups, and the
incidence rate of
complications and the
recurrence rate at 3mo
after treatment were statistically analyzed.<p>
RESULTS:
There were significant differences in the BCVA and CMT between the two groups at different
time points of
treatment(<i>P</i><0.05), and the BCVA in
observation group at different
time points
after treatment was higher than that in
control group while the CMT was lower than that in
control group(<i>P</i><0.05). There was no significant difference in
intraocular pressure between the two groups at different
time points of
treatment(<i>P</i>>0.05). The
visual acuity and ME improvement effects in
observation group were better than those in
control group, and the
metamorphopsia and
hemorrhage exudation
absorption were better than those in
control group(<i>P</i><0.05). There were no significant difference in the
incidence rate of
complications and the
recurrence rate at 3mo
after treatment between the two groups(<i>P</i>>0.05).<p>
CONCLUSION:
Yiqihuoxuehuayu decoction combined with
triamcinolone acetonide and 532nm
argon laser has definite
efficacy in the
treatment of ME
secondary to BRVO, and it can improve
visual acuity, reduce
macular edema and promote fundus
hemorrhage exudation
absorption, and it has high
safety.