Serum anti-Mullerian hormone levels as a predictor of the ovarian response and IVF outcomes / 대한생식의학회지
Clinical and Experimental Reproductive Medicine
; : 153-158, 2011.
Article
在 En
| WPRIM
| ID: wpr-78196
Responsible library:
WPRO
ABSTRACT
OBJECTIVE:
The aim of this study was to investigate whether anti-Mullerian hormone (AMH) levels could be predict ovarian poor/hyper response and IVF cycle outcome.METHODS:
Between May 2010 and January 2011, serum AMH levels were evaluated with retrospective analysis. Three hundred seventy infertile women undergoing 461 IVF cycles between the ages of 20 and 42 were studied. We defined the poor response as the number of oocytes retrieved was equal or less than 3, and the hyper response as more than 25 oocytes retrieved. Serum AMH was measured by commercial enzyme-linked immunoassay.RESULTS:
The number of oocytes retrieved was more correlated with the serum AMH level (r=0.781, p3.55 ng/mL), the groups showed no statistical differences in mature oocyte rates (71.6% vs. 76.5% vs. 74.8%) or fertilization rates (76.9% vs. 76.6% vs. 73.8%), but showed significant differences in clinical pregnancy rates (21.7% vs. 24.1% vs. 40.8%, p=0.017).CONCLUSION:
The serum AMH level can be used to predict the number of oocytes retrieved in patients, distinguishing poor and high responders.Key words
全文:
1
索引:
WPRIM
主要主题:
Oocytes
/
Fertilization in Vitro
/
Retrospective Studies
/
Sensitivity and Specificity
/
Pregnancy Rate
/
Anti-Mullerian Hormone
/
Fertilization
研究类型:
Diagnostic_studies
/
Observational_studies
/
Prognostic_studies
限制:
Female
/
Humans
语言:
En
期刊:
Clinical and Experimental Reproductive Medicine
年:
2011
类型:
Article