The effect of soy isoflavones on early high altitude polycythemia: A multicenter clinical study of 80 cases / 解放军医学杂志

ABSTRACT

Objective To evaluate the efficacy and safety of oxygen inhalation combined with oral administration of soy isoflavones on people who migrated from plains to high altitude area suffering from polycythemia. Methods Eighty young men, who migrated to the area of altitude of 3500~5300m for more than ten months, and their hemoglobin (HGB) level was verified in the range of 190g/L≤HGB 0.05). Multiple linear regression analysis revealed that the affecting factors of HGB that the change in HGB values was significantly associated with test grouping. In addition, there were no obvious side effects and changes in BP, ECG, chest X-ray, liver and kidney functions before and after soy isoflavones intake. Conclusion In high-altitude area, oxygen and oral administration of soy isoflavones are safe and more effective measure in the early prevention of high altitude polycythemia.