Chemical constituents from leaves of Elaeagnus mollis / 中草药

ABSTRACT

Objective: To study the chemical constituents in the leaves of Elaeagnus mollis. Methods: Their structures were identified on the basis of silica gel column chromatography and Sephadex LH-20 gel column chromatography, and HPLC methods were used for the separation and purification of chemical constituents. Results: Sixteen compounds were isolated from 70% ethanol extracts of the leaves of E. mollis. The structures were identified as kaempferol-3-O-β-D-glucopyranoside (1), kaempferol-3-O-(6″-O-trans-p-coumaroyl)-β-D- glucopyranoside (2), kaempferol-3-O-(6″-O-cis-p-coumaroyl)-β-D-glucopyranoside (3), quercetin-3-O-α-L-arabinopyranoside (4), kaempferol-7-O-α-L-rhamnopyranoside (5), kaempferol-3,7-di-O-α-L-rhamnopyranoside (6), kaempferol-3-O-β-D-galactopyranosyl-7- O-α-L-rhamnopyranoside (7), kaempferol-3-O-α-Larabinofuranosyl-7-O-α-L-rhamnopyranoside (8), hippophamide (9), L-tryptophan (10), arjunolicacid (11), ursolicacid (12), kaempferol (13), rutin (14), adenosine (15), and β-daucosterol (16). Conclusion: Compounds 3-10 and 15 are isolated from the plants of Elaeagnus L. for the first time. Compounds 1, 2, 11, and 12 are isolated from this plant for the first time.