ABSTRACT
Objective:
To compare the value of
digital breast tomosynthesis (DBT) and flly-field
digital mammography (FFDM) in evaluating
breast architectural distortion (AD) lesions, and the value of DBT and ultrasound in differentiating benign and malignant
breast AD.
Methods:
DBT, FFDM and ultrasound data of 58
patients with AD lesions detected with DBT were retrospectively analyzed. Taken pathological outcomes as
standards, the
sensitivity,
specificity and accuracy of DBT and FFDM in evaluating
breast AD were compared and analyzed. The consistency of results of DBT and ultrasound in differentiating benign and malignant
breast AD with pathological results was analyzed.
ROC curve of DBT and ultrasound for differentiating benign and malignant
breast AD were drawn, and the diagnostic efficacies were compared.
Results:
All
patients underwent FFDM, and 41 of them also underwent ultrasound examination. Among 58 cases of
breast AD detected with DBT, only 23 AD were found with FFDM (χ2=33.03, P0.05). Median consistency of DBT and ultrasound results was observed in differentiating benign and malignant
breast AD and pathological results (Kappa=0.65, 0.71, both P0.05).
Conclusion:
The
sensitivity and accuracy of DBT in evaluating
breast AD are higher than FFDM. DBT is comparable to ultrasound in differentiating benign and malignant
breast AD. AD detected with DBT has relatively high
malignancy, so it is recommended to conduct timely
biopsy for correct
diagnosis.