Clinical significance of pathological subtypes in the intraductal papillary mucinous neoplasm of the pancreas / 中华消化外科杂志

ABSTRACT

The intraductal papillary mucinous neoplasm (IPMN) of the pancreas is a group of the rare pancreatic cyst neoplasms which characterized by intraductal proliferation of neoplastic mucinous cells with various degree of atypia. According to pancreatic duct invasion, the IPMN of the pancreas could be classified as main duct, branch duct and mixed duct subtypes which pathologically could be as adenoma to invasive tumors. Based on the cytomorphological features of the papillae and the immunohistochemical features of the mucin glycoproteins, the IPMN of the pancreas could be distinguished as gastric, intestinal, pancreatobiliary and oncocytic subtypes. In this article, the authors will discuss on the the clinical significance of pathological subtypes in the IPMN of the pancreas based on the review of the recent articles and their experience, in order to improve the knowledge on the different subtypes of IPMN.