ABSTRACT
AIM:
To comparatively analyze the
efficacy of subthreshold
laser photocoagulation with the NAVILAS®
Laser system and subthreshold micropulse
laser for
patients with chronic
central serous chorioretinopathy(cCSC).
METHODS:
A retrospective
clinical study. A total of 36
patients(40
eyes)with cCSC were recruited from January 2020 to January 2021 diagnosed at the Affiliated
Eye Hospital of Nanjing Medical
University. There were 19
patients(23
eyes)treated with subthreshold navigated
laser photocoagulation(the Navilas group), and 17
patients(17
eyes)treated with subthreshold micropulse
laser(SML)(the SML group). There was no significant difference in baseline data between the two groups(P>0.05). The best corrected
visual acuity(BCVA, LogMAR), central macular thickness(CMT),
subretinal fluid(SRF)height, vessel densities of the superficial
capillary plexus(SCP), the deep
capillary plexus(DCP)and area of the foveal avascular zone(FAZ)were collected at 2wk, 1, 3 and 6mo before and
after treatment.
RESULTS:
The BCVA of the two groups were significantly higher than that before
treatment at 3 and 6mo after
surgery(P<0.05),which was significantly reduced at 2wk
after treatment in the Navilas group and was reduced at 1mo
after treatment in the SML group(P<0.05). In both groups, there was significant decrease compared with that before
treatment at 3 and 6mo
after treatment(P<0.05),but there was no significant difference between the two groups(P>0.05). The difference in SRF
absorption between the two groups was statistically significant(P<0.05), and the complete
absorption rate of SRF in the Navilas group was higher than that in the SML group. SCP, DCP, the area of the FAZ were not significantly different from each
time ofbaseline in the two groups(P >0.05).
CONCLUSION:
Subthreshold
laser photocoagulation with the NAVILAS&#xAE;
Laser system can rapidly improve the
retinal morphology and shorten the
course of cCSC to improve the recovery of visual function with its rapid effect, high
cost-
effectiveness, non-invasiveness and high repeatability, which can be a new clinical
method for
patients with cCSC.