Research progress in risk prediction of acute exacerbations of chronic obstructive pulmonary disease / 中国医师杂志

ABSTRACT

Chronic obstructive pulmonary disease (COPD) is a chronic respiratory disease characterized by persistent respiratory symptoms and airflow limitation. Acut exacerbations (AE) are one of the main outcomes in patients with COPD. AE of COPD will accelerate hospitalization rates, increase mortality, and reduce quality of life. Therefore, it is of importance to identify predictors of AE in patients with COPD. This review mainly summarizes the predictive factors associated with AE from the clinical characteristics of patients, biomarkers, and composite index prediction models.