ABSTRACT
Purpose@#To
report two cases of paraproteinemic keratopathy (PK).Case
summary:
A 57-year-old man visited the
ophthalmology clinic complaining of decreased
visual acuity since 1 year earlier.
White crystalline deposits were observed on both
corneas and the best corrected
visual acuity (BCVA) of both
eyes was 1.0. After 3 months, the BCVA decreased to 0.8 in the right and 0.6 in the left. Increased corneal deposits were observed. To rule out PK, his
medical records were checked. The
patient had been diagnosed with lymphoplasmacytic
lymphoma 3 years earlier. Diagnosing PK, the
patient was referred
back to the Hemato-Oncology department. After 3 months of
chemotherapy, the corneal deposits decreased and BCVA returned to 1.0. A 69-year-old
woman presented complaining of decreased
visual acuity for 2 years. The uncorrected
visual acuity (UCVA) was 0.4 in the right and
finger count at 30 cm in the left. Brown deposits were observed on both
corneas and
lenses. The
serum copper level was elevated. She was referred to the
internal medicine department and diagnosed with
multiple myeloma.
After treatment, the
laboratory results returned to normal, but the UCVA decreased to
hand motion in the left. A left
white cataract was noted and
cataract surgery was performed. 1 month postoperatively, the BCVA was 0.9, with no change in the corneal deposits. @*Conclusions@#When there are corneal deposits, we should consider PK in the
differential diagnosis. In such cases, systemic
treatment is the first line. Therefore, diagnosing and referring PK
patients to the
internal medicine department is crucial.