ABSTRACT
Objective:
To understand and analyze the
incidence of
club drug abuse and influencing factors in men who have sex with men (MSM) in Qingdao, and provide reference for the
AIDS prevention and intervention in this
population.
Methods:
From March 2017 to July 31, 2022, MSM
who did not abuse
club drug were recruited by snowball sampling of MSM social
organizations in Qingdao, a prospective cohort was established, and a follow-up
survey was conducted every 6 months. The
survey collected the information about the MSM's demographic characteristics, sexual characteristics,
club drug abuse and others. The
incidence of
club drug abuse was the outcome dependent variable and the interval between the recruitment into the cohort and the
incidence of
club drug abuse was the
time dependent variable. Cox
regression analysis was conducted to identify the influencing factors for
club drug abuse.
Results:
A total of 509 MSM were recruited at
baseline survey, and 369 eligible MSM were enrolled in this cohort. A total of 62 MSM began to abuse
club drug during the study period, and the cumulative follow-up
time was 911.54
person-years, the
incidence of
club drug abuse was 6.80/100
person-years. All the
club drug abusers
shared drugs with others in the first
club drug abuse, and 16.13% (10/62) had mix-use of
club drugs. The multivariate Cox proportional
risk regression analysis showed that being
students (aHR=2.17, 95%CI 1.15-4.10), receiving no
HIV testing or receiving 1
HIV testing during past 6 months (aHR=4.57, 95%CI1.80-11.60; aHR=5.15, 95%CI 2.83-9.36), having
sex only with regular
sexual partners during past 6 months (aHR=4.75,95%CI2.32-9.75), having more than 4
homosexual partners (aHR=1.70, 95%CI1.01-2.87) and abuse of
club drug of
sexual partners during past 6 months (aHR=12.78, 95%CI3.06-53.35) were significantly associated with
club drug abuse in the MSM.
Conclusions:
The
incidence of
club drug abuse was at a high level in the MSM cohort in Qingdao, indicating a high
risk for
HIV infection. Being
student, receiving less
HIV testing, having
sex only with regular
sexual partners, having more
homosexual partners and abuse of
club drug of
sexual partners during past 6 months were
risk factors for the
incidence of
club drug abuse in the MSM. Targeted
surveillance and intervention
measures should be strengthened to reduce the
risk of
club drug abuse in MSM.