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Proceedings of the ACM on Human-Computer Interaction ; 5(CHIPLAY), 2021.
Article in English | Scopus | ID: covidwho-1480309

ABSTRACT

COVID-19 exposed the need to identify newer tools to understand perception of information, behavioral conformance to instructions and model the effects of individual motivation and decisions on the success of measures being put in place. We approach this challenge through the lens of serious games. Serious games are designed to instruct and inform within the confines of their magic circle. We built a multiplayer serious game, Point of Contact (PoC), to investigate effects of a serious game on perception and behavior. We conducted a study with 23 participants to gauge perceptions of COVID-19 preventive measures and quantify the change after playing PoC. The results show a significant positive change to participants' perceptions towards COVID-19 preventive measures, shifting perceptions towards following guidelines more strictly due to a greater awareness of how the virus spreads. We discuss these implications and the value of a serious game like PoC towards pandemic risk modelling at a microcosm level. © 2021 ACM.

2.
Journal of Clinical and Diagnostic Research ; 15(10):PD12-PD13, 2021.
Article in English | EMBASE | ID: covidwho-1478459

ABSTRACT

Malrotation of small bowel with midgut volvulus has a very low incidence of 0.2% in adults. Symptomatic malrotation in neonates occur in one in 6000 live births. The normal 270 degrees counter-clockwise gut rotation around the axis of superior mesenteric artery is absent in such cases. A 20-year-old male presented with intermittent colicky abdominal pain since four to five months, post-prandial bilious vomiting since one week and obstipation since two days. He also had difficulty breathing since two days. Abdominal examination revealed vague lump in right lower abdomen with no signs of peritonitis. Radiological investigations Ultrasonography (USG) and Contrast Enhanced Computed Tomography (CECT) abdomen demonstrated over distended stomach with dilated D1 and D2 showing changes in relation to superior mesenteric artery and superior mesenteric vein with rotation of mesentery in whirlpool pattern. His Reverse Transcriptase-Polymerase Chain Reaction Test (RT-PCR) was positive for Coronavirus Disease-2019 (COVID-19). Conservative trial for two days was followed by surgical exploration which revealed gut malrotation with mid-gut volvulus. Ladd's procedure was performed. Malrotation with midgut volvulus is an acute surgical emergency that demands high index of suspicion in an adult. Associated COVID-19 pneumonia can increase mortality. Patient was followed-up after three weeks with fruitful results, proving that an early diagnosis and definitive surgical correction of malrotation with midgut volvulus is essential.

3.
J. Pharm. Res. Int. ; 33(41B):335-351, 2021.
Article in English | Web of Science | ID: covidwho-1459041

ABSTRACT

The advent of antibiotics in the 19th century has significantly reduced the morbidity and mortality of infectious diseases. However, irrational use of antibiotics in humans as well as in animals has driven the 21st century to the rapid emergence of MultiDrug Resistance Bacteria (MRB). Moreover, the dissemination of COVID-19 pandemic has paved the way for MRB, typically due to increased use of antibiotics to avoid secondary infections. The fast pace progression of bacterial resistance for the antibiotics and their combinations is making the management of MRB infections tough and increasing the cost of the treatment as well. However, use of Efflux Pump Inhibitors (EPI) as adjuvant for antibiotics has shown a ray of hope by retaining the susceptibility of the antibiotics and thereby reducing the burden of immediate requirement of new antibiotics for MRB. Accordingly, the present paper is aimed to scrutinize the predominant literature depicting the plant Phyto-constituents as an EPI and adjuvant for antibiotics in the management of MRB infections. The systematic review of the present paper indicates that the plant phyto-constituents belonging to the class of alkaloids, terpenoids, flavonoids can effectively be used as EPIs for antibiotics such as Ciprofloxacin, Norfloxacin, Tetracyclines and Chloramphenicol. Bibliometric analysis indicates that the Journal of Antimicrobial Chemotherapy, Antimicrobial Agents and Chemotherapy and BMC Complementary & Alternative Medicine have published impactful articles on EPI potential of plant phyto-constituents. Further, authors Kuete V, Dzotam JK, Falcao-silva VD, Gibbons S, Kuiate JR, Mbaveng AT, Tankeo SB and Voukeng IK are the major contributors and productive authors.

4.
Economic and Political Weekly ; 55:36, 2020.
Article in English | GIM | ID: covidwho-911235

ABSTRACT

This article is on the spread of the coronavirus pandemic in the city of Mumbai with the pandemic considered as a local public bad with spillover effects across the wards of the city. Spatial econometric techniques are used to model these spillovers using both cross-section as well as panel data. The main conclusion of the article is that the significant spatial spillover effect across the wards of the city is likely to make the exit from the enforced lockdown a major challenge.

5.
Economic and Political Weekly ; 55(36):15-20, 2020.
Article in English | Scopus | ID: covidwho-855506

ABSTRACT

This article is on the spread of the coronavirus pandemic in the city of Mumbai with the pandemic considered as a local public bad with spillover effects across the wards of the city. Spatial econometric techniques are used to model these spillovers using both cross-section as well as panel data. The main conclusion of the article is that the significant spatial spillover effect across the wards of the city is likely to make the exit from the enforced lockdown a major challenge. © 2020 Economic and Political Weekly. All rights reserved.

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