Your browser doesn't support javascript.
Show: 20 | 50 | 100
Results 1 - 2 de 2
Laryngoscope ; 131(9): 1927-1929, 2021 09.
Article in English | MEDLINE | ID: covidwho-1083297


The nasopharyngeal swab has been used with increased frequency since the beginning of the COVID-19 pandemic. Little has been written in the literature regarding the complications arising from this procedure, as it is generally accepted as safe. In this report, we describe a case in which a young woman sustained a traumatic skull base injury during a nasopharyngeal swab for COVID-19. We then discuss the subsequent treatment and outcome. This case demonstrates the potential for significant complications arising from this widespread procedure and the necessity for awareness of these potential complications. Laryngoscope, 131:1927-1929, 2021.

COVID-19 Testing , COVID-19/diagnosis , Cerebrospinal Fluid Leak/etiology , Encephalocele/etiology , Skull Base/injuries , Adult , Encephalocele/diagnostic imaging , Female , Humans , Magnetic Resonance Imaging , Nasopharynx , Skull Base/diagnostic imaging , Skull Base/surgery , Tomography, X-Ray Computed
J Neuroinflammation ; 17(1): 286, 2020 Sep 30.
Article in English | MEDLINE | ID: covidwho-808484


The coronavirus disease-19 (COVID-19) pandemic is an unprecedented worldwide health crisis. COVID-19 is caused by SARS-CoV-2, a highly infectious pathogen that is genetically similar to SARS-CoV. Similar to other recent coronavirus outbreaks, including SARS and MERS, SARS-CoV-2 infected patients typically present with fever, dry cough, fatigue, and lower respiratory system dysfunction, including high rates of pneumonia and acute respiratory distress syndrome (ARDS); however, a rapidly accumulating set of clinical studies revealed atypical symptoms of COVID-19 that involve neurological signs, including headaches, anosmia, nausea, dysgeusia, damage to respiratory centers, and cerebral infarction. These unexpected findings may provide important clues regarding the pathological sequela of SARS-CoV-2 infection. Moreover, no efficacious therapies or vaccines are currently available, complicating the clinical management of COVID-19 patients and emphasizing the public health need for controlled, hypothesis-driven experimental studies to provide a framework for therapeutic development. In this mini-review, we summarize the current body of literature regarding the central nervous system (CNS) effects of SARS-CoV-2 and discuss several potential targets for therapeutic development to reduce neurological consequences in COVID-19 patients.

Coronavirus Infections/complications , Nervous System Diseases/virology , Pneumonia, Viral/complications , Betacoronavirus , COVID-19 , Humans , Pandemics , SARS-CoV-2