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2.
Nurs Stand ; 35(5): 45-50, 2020 04 29.
Article in English | MEDLINE | ID: covidwho-1835710

ABSTRACT

Decontamination using hand hygiene remains one of the most important and effective methods for reducing healthcare-associated infections and cross-infection between patients. In 1860, Florence Nightingale wrote that nurses should wash their hands frequently throughout the day, demonstrating an early awareness of the effectiveness of this simple procedure. The COVID-19 pandemic has demonstrated that effectively applied hand hygiene is a vital intervention that can be used to prevent the spread of disease. This article details the correct procedure required for effective hand hygiene and emphasises the need for nurses to keep up to date with evidence-based guidelines. The article also outlines the differences between hand decontamination using alcohol-based hand gels and soap and water, and the complex factors that can interfere with effective hand hygiene compliance.


Subject(s)
Coronavirus Infections/prevention & control , Cross Infection , Guideline Adherence , Hand Hygiene , Infection Control , Pandemics/prevention & control , Pneumonia, Viral/prevention & control , Betacoronavirus , COVID-19 , Coronavirus Infections/epidemiology , Coronavirus Infections/transmission , Cross Infection/prevention & control , Hand Disinfection/methods , Humans , Infection Control/methods , Pneumonia, Viral/epidemiology , Pneumonia, Viral/transmission , SARS-CoV-2
3.
Turk Kardiyol Dern Ars ; 48(Suppl 1): 1-48, 2020 03.
Article in Turkish | MEDLINE | ID: covidwho-1835514

ABSTRACT

In December 2019, in the city of Wuhan, in the Hubei province of China, treatment-resistant cases of pneumonia emerged and spread rapidly for reasons unknown. A new strain of coronavirus (severe acute respiratory syndrome coronavirus-2 [SARS-CoV-2]) was identified and caused the first pandemic of the 21st century. The virus was officially detected in our country on March 11, 2020, and the number of cases increased rapidly; the virus was isolated in 670 patients within 10 days. The rapid increase in the number of patients has required our physicians to learn to protect both the public and themselves when treating patients with this highly infectious disease. The group most affected by the outbreak and with the highest mortality rate is elderly patients with known cardiovascular disease. Therefore, it is necessary for cardiology specialists to take an active role in combating the epidemic. The aim of this article is to make a brief assessment of current information regarding the management of cardiovascular patients affected by COVID-19 and to provide practical suggestions to cardiology specialists about problems and questions they have frequently encountered.


Subject(s)
Betacoronavirus , Cardiology/standards , Cardiovascular Diseases/therapy , Cardiovascular Diseases/virology , Coronavirus Infections/epidemiology , Pneumonia, Viral/epidemiology , COVID-19 , Cardiovascular Diseases/epidemiology , Consensus , Humans , Pandemics , SARS-CoV-2 , Societies, Medical , Turkey
4.
Turk Kardiyol Dern Ars ; 48(Suppl 1): 1-87, 2020 05.
Article in Turkish | MEDLINE | ID: covidwho-1835513

ABSTRACT

In December 2019, in the city of Wuhan, in the Hubei province of China, treatment-resistant cases of pneumonia emerged and spread rapidly for reasons unknown. A new strain of coronavirus (severe acute respiratory syndrome coronavirus-2 [SARS-CoV-2]) was identified and caused the first pandemic of the 21st century. The virus was officially detected in our country on March 11, 2020, and the number of cases increased rapidly; the virus was isolated in 670 patients within 10 days. The rapid increase in the number of patients has required our physicians to learn to protect both the public and themselves when treating patients with this highly infectious disease. The group most affected by the outbreak and with the highest mortality rate is elderly patients with known cardiovascular disease. Therefore, it is necessary for cardiology specialists to take an active role in combating the epidemic. The aim of this article is to make a brief assessment of current information regarding the management of cardiovascular patients affected by COVID-19 and to provide practical suggestions to cardiology specialists about problems and questions they have frequently encountered.


Subject(s)
Cardiovascular Diseases , Coronavirus Infections , Pandemics , Pneumonia, Viral , Betacoronavirus , COVID-19 , Cardiology/standards , Cardiovascular Diseases/complications , Cardiovascular Diseases/therapy , Consensus , Coronavirus Infections/complications , Coronavirus Infections/epidemiology , Humans , Pneumonia, Viral/complications , Pneumonia, Viral/epidemiology , Practice Guidelines as Topic , SARS-CoV-2
6.
Nat Rev Immunol ; 20(7): 442-447, 2020 07.
Article in English | MEDLINE | ID: covidwho-1830064

ABSTRACT

A male bias in mortality has emerged in the COVID-19 pandemic, which is consistent with the pathogenesis of other viral infections. Biological sex differences may manifest themselves in susceptibility to infection, early pathogenesis, innate viral control, adaptive immune responses or the balance of inflammation and tissue repair in the resolution of infection. We discuss available sex-disaggregated epidemiological data from the COVID-19 pandemic, introduce sex-differential features of immunity and highlight potential sex differences underlying COVID-19 severity. We propose that sex differences in immunopathogenesis will inform mechanisms of COVID-19, identify points for therapeutic intervention and improve vaccine design and increase vaccine efficacy.


Subject(s)
Coronavirus Infections/epidemiology , Pneumonia, Viral/epidemiology , Adaptive Immunity , Age Factors , Betacoronavirus/physiology , COVID-19 , Coronavirus Infections/immunology , Coronavirus Infections/pathology , Coronavirus Infections/physiopathology , Female , Humans , Interferons/immunology , Male , Pandemics , Pneumonia, Viral/immunology , Pneumonia, Viral/pathology , Pneumonia, Viral/physiopathology , SARS-CoV-2 , Severity of Illness Index , Sex Factors , Sociological Factors
8.
J Diabetes Complications ; 34(9): 107637, 2020 09.
Article in English | MEDLINE | ID: covidwho-1828813

ABSTRACT

BACKGROUND: The novel coronavirus SARS-CoV-2 has taken the world by storm. Alongside COVID-19, diabetes is a long-standing global epidemic. The diabetes population has been reported to suffer adverse outcomes if infected by COVID-19. The aim was to summarise information and resources available on diabetes and COVID-19, highlighting special measures that individuals with diabetes need to follow. METHODS: A search using keywords "COVID-19" and "Diabetes" was performed using different sources, including PubMed and World Health Organization. RESULTS: COVID-19 may enhance complications in individuals with diabetes through an imbalance in angiotension-converting enzyme 2 (ACE2) activation pathways leading to an inflammatory response. ACE2 imbalance in the pancreas causes acute ß-cell dysfunction and a resultant hyperglycemic state. These individuals may be prone to worsened COVID-19 complications including vasculopathy, coagulopathy as well as psychological stress. Apart from general preventive measures, remaining hydrated, monitoring blood glucose regularly and monitoring ketone bodies in urine if on insulin is essential. All this while concurrently maintaining physical activity and a healthy diet. Different supporting entities are being set up to help this population. CONCLUSION: COVID-19 is a top priority. It is important to remember that a substantial proportion of the world's population is affected by other co-morbidities such as diabetes. These require special attention during this pandemic to avoid adding on to the burden of countries' healthcare systems.


Subject(s)
Betacoronavirus , Coronavirus Infections/epidemiology , Coronavirus Infections/prevention & control , Diabetes Mellitus/epidemiology , Diabetes Mellitus/therapy , Pandemics/prevention & control , Pneumonia, Viral/epidemiology , Pneumonia, Viral/prevention & control , COVID-19 , Humans , SARS-CoV-2
9.
Knee Surg Sports Traumatol Arthrosc ; 28(6): 1712-1719, 2020 Jun.
Article in English | MEDLINE | ID: covidwho-1826408

ABSTRACT

PURPOSE: The aim of the present study was to evaluate the impact of the coronavirus (COVID-19) pandemic on joint arthroplasty service in Europe by conducting an online survey of arthroplasty surgeons. METHODS: The survey was conducted in the European Hip Society (EHS) and the European Knee Associates (EKA). The survey consisted of 20 questions (single, multiple choice, ranked). Four topics were addressed: (1) origin and surgical experience of the participant (four questions); (2) potential disruption of arthroplasty surgeries (12 questions); (3) influence of the COVID-19 pandemic on the particular arthroplasty surgeon (four questions); (4) a matrix provided 14 different arthroplasty surgeries and the participant was asked to state whether dedicated surgery was stopped, delayed or cancelled. RESULTS: Two-hundred and seventy-two surgeons (217 EHS, 55 EKA) from 40 different countries participated. Of the respondents, 25.7% stated that all surgeries were cancelled in their departments, while 68.4% responded that elective inpatient procedures were no longer being performed. With regard to the specific surgical procedures, nearly all primary TJA were cancelled (92.6%) as well as aseptic revisions (94.7%). In most hospitals, periprosthetic fractures (87.2%), hip arthroplasty for femoral neck fractures and septic revisions for acute infections (75.8%) were still being performed. CONCLUSION: During the current 2020 COVID-19 pandemic, we are experiencing a near-total shutdown of TJA. A massive cutback was observed for primary TJA and revision TJA, even in massively failed TJA with collapse, dislocation, component failure or imminent dislocation. Only life-threatening pathologies like periprosthetic fractures and acute septic TJA are currently undergoing surgical treatment. LEVEL OF EVIDENCE: V.


Subject(s)
Betacoronavirus , Coronavirus Infections/epidemiology , Delivery of Health Care/statistics & numerical data , Elective Surgical Procedures/statistics & numerical data , Orthopedic Procedures/statistics & numerical data , Pandemics , Pneumonia, Viral/epidemiology , COVID-19 , Europe/epidemiology , Health Care Surveys , Humans , Internet , Male , Prospective Studies , SARS-CoV-2
10.
Knee Surg Sports Traumatol Arthrosc ; 28(6): 1705-1711, 2020 Jun.
Article in English | MEDLINE | ID: covidwho-1826407

ABSTRACT

PURPOSE: Due to the lack of evidence, it was the aim of the study to investigate current possible cutbacks in orthopaedic healthcare due to the coronavirus disease 2019 pandemic (COVID-19). METHODS: An online survey was performed of orthopaedic surgeons in the German-speaking Arthroscopy Society (Gesellschaft für Arthroskopie und Gelenkchirurgie, AGA). The survey consisted of 20 questions concerning four topics: four questions addressed the origin and surgical experience of the participant, 12 questions dealt with potential cutbacks in orthopaedic healthcare and 4 questions addressed the influence of the pandemic on the particular surgeon. RESULTS: Of 4234 contacted orthopaedic surgeons, 1399 responded. Regarding arthroscopic procedures between 10 and 30% of the participants stated that these were still being performed-with actual percentages depending on the specific joint and procedure. Only 6.2% of the participants stated that elective total joint arthroplasty was still being performed at their centre. In addition, physical rehabilitation and surgeons' postoperative follow-ups were severely affected. CONCLUSION: Orthopaedic healthcare services in Austria, Germany, and Switzerland are suffering a drastic cutback due to COVID-19. A drastic reduction in arthroscopic procedures like rotator cuff repair and cruciate ligament reconstruction and an almost total shutdown of elective total joint arthroplasty were reported. Long-term consequences cannot be predicted yet. The described disruption in orthopaedic healthcare services has to be viewed as historic. LEVEL OF EVIDENCE: V.


Subject(s)
Coronavirus Infections/epidemiology , Delivery of Health Care/statistics & numerical data , Elective Surgical Procedures/statistics & numerical data , Orthopedic Procedures/statistics & numerical data , Orthopedics/statistics & numerical data , Pneumonia, Viral/epidemiology , Aftercare/statistics & numerical data , Arthroplasty/statistics & numerical data , Arthroscopy/statistics & numerical data , Austria/epidemiology , Betacoronavirus , COVID-19 , Coronavirus Infections/virology , Germany/epidemiology , Health Care Surveys , Humans , Internet , Male , Pandemics/statistics & numerical data , Pneumonia, Viral/virology , Rehabilitation/statistics & numerical data , SARS-CoV-2 , Switzerland/epidemiology
12.
rev. cuid. (Bucaramanga. 2010) ; 12(2): 1-12, mayo 1, 2021.
Article in Portuguese | WHO COVID, LILACS (Americas) | ID: covidwho-1811612

ABSTRACT

Introdução: Devido as iniquidades históricas, o contexto pandêmico do COVID-19 tem impactado de maneira distinta os segmentos sociais, exigindo um acompanhamento especial às minorias étnico-raciais que vivem em situação de vulnerabilidade. Nesse sentido, o estudo tem como objetivo analisar a vulnerabilidade da população negra brasileira frente à evolução da pandemia por COVID-19. Materiais e Métodos: Trata-se de um estudo documental, descritivo, quantitativo, realizada a partir dos boletins epidemiológicos coronavírus publicados pelo Ministério da Saúde do Brasil. Foram avaliadas duas variáveis dos boletins epidemiológicos coronavírus a partir da raça/cor: hospitalizações por síndrome respiratória aguda grave e óbito por Covid-19. Resultados: Entre os boletins nº 9 e nº 18 evidenciou-se o aumento sustentado nas taxas de internação por síndrome respiratória aguda grave (de 23,9% para 54,7%) e óbito (de 34,3% para 61,3%) entre pessoas de raça/cor negra e redução constante na hospitalização (de 73% para 43,3%) e óbito (de 62,9% para 36,5%) entre pessoas brancas. Constata-se que pessoas negras têm maiores chances de internação por SRAG e morte por COVID-19 no Brasil, o que implica maior situação de vulnerabilidade. Discussão: Acredita-se que esse cenário desfavorável entre pessoas negras se deve a dificuldade ou impossibilidade de realização de isolamento social, à prevalência de comorbidades que precipitam quadros graves do COVID-19, as dificuldades no acesso aos serviços de saúde e ao racismo institucional. Conclusão: faz-se necessário a implementação de uma rede de proteção social a esse grupo racial, com o objetivo de reduzir o acometimento da doença e a letalidade do vírus.


Introduction: Due to the historical inequality, the COVID-19 pandemic has impacted social groups differently, which calls for special assistance to ethnic-racial minorities living in a situation of vulnerability. In light of this, this study is aimed to analyze the vulnerability of the black population in Brazil to the evolution of the COVID-19 pandemic. Materials and Methods: A quantitative descriptive study following a documentary method was conducted based on the coronavirus disease epidemiological bulletins published by the Brazilian Ministry of Health. Two variables were assessed from epidemiological bulletins regarding race/color: hospitalizations for severe acute respiratory syndrome and deaths due to COVID-19. Results: A steady increase in rates of hospitalization for severe acute respiratory syndrome (from 23.9% to 54.7%) and death (from 34.3% to 61.3%) was observed among the black population in bulletins 9-18, contrary to the steady decrease in rates of hospitalization (from 73% to 43.3%) and death (from 6.29% to 36.5%) among the white people. It was also found that black people are more likely to be hospitalized for SARS infection and death due to COVID-19 in Brazil, suggesting that they are at a higher vulnerability. Discussion: This unfavorable scenario for the black population is considered to arise from the difficulty or impossibility of social integration, the prevalence of comorbidities that trigger severe COVID-19 forms, difficulties in accessing healthcare services and institutional racism. Conclusion: The implementation of a social protection network is necessary to reduce the disease infection and the mortality of the virus.


Introducción: Debido a la inequidad histórica existente, la pandemia del COVID-19 ha impactado a los grupos sociales de forma diferente, lo que exige un acompañamiento especial a las minorías étnico-raciales que viven en situación de vulnerabilidad. En este sentido, el presente estudio tiene como objetivo analizar la vulnerabilidad de la población negra brasileña frente a la evolución de la pandemia por COVID-19. Materiales y métodos: Se realizó un estudio documental descriptivo de enfoque cuantitativo a partir de los boletines epidemiológicos sobre coronavirus publicados por el Ministerio de Salud de Brasil. Se evaluaron dos variables en los boletines epidemiológicos con base en la raza/color: hospitalizaciones por síndrome respiratorio agudo grave y muertes por COVID-19. Resultados: Entre los boletines 9 y 18 se evidenció un aumento sostenido de las tasas de hospitalización por síndrome respiratorio agudo grave (del 23.9% al 54.7%) y de muerte (del 34.3% al 61.3%) entre la población negra, así como una reducción constante de la tasa de hospitalización (del 73% al 43.3%) y de muerte (del 62.9% al 36.5%) entre la población blanca. Se observó que las personas de raza negra tienen una mayor probabilidad de hospitalización por infección por SARS y muerte por COVID-19 en Brasil, lo que supone que se encuentran en una mayor situación de vulnerabilidad. Discusión: Se considera que este escenario desfavorable para las personas de raza negra se debe a la dificultad o imposibilidad de integración social, la prevalencia de comorbilidades que desencadenan cuadros graves de COVID-19, las dificultades de acceso a los servicios de salud y el racismo institucional. Conclusión: Se hace necesaria la implementación de una red de protección social para este grupo racial a fin de reducir el contagio de la enfermedad y la letalidad del virus.


Subject(s)
Humans , Male , Female , African Continental Ancestry Group , Racism , Betacoronavirus
14.
Lancet Infect Dis ; 20(7): 775-776, 2020 07.
Article in English | MEDLINE | ID: covidwho-1778518
16.
Can J Anaesth ; 67(10): 1424-1430, 2020 Oct.
Article in English | MEDLINE | ID: covidwho-1777852

ABSTRACT

PURPOSE: Risk to healthcare workers treating asymptomatic patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the operating room depends on multiple factors. This review examines the evidence for asymptomatic or pre-symptomatic carriage of SARS-CoV-2, the risk of transmission from asymptomatic patients, and the specific risks associated with aerosol-generating procedures. Protective measures, such as minimization of aerosols and use of personal protective equipment in the setting of treating asymptomatic patients, are also reviewed. SOURCE: We examined the published literature as well as Societal guidelines. PRINCIPAL FINDINGS: There is evidence that a proportion of those infected with SARS-CoV-2 have detectable viral loads prior to exhibiting symptoms, or without ever developing symptoms. The degree of risk of transmission from asymptomatic patients to healthcare providers will depend on the prevalence of disease in the population, which is difficult to assess without widespread population screening. Aerosol-generating procedures increase the odds of viral transmission from infected symptomatic patients to healthcare providers, but transmission from asymptomatic patients has not been reported. Techniques to minimize aerosolization and appropriate personal protective equipment may help reduce the risk to healthcare workers in the operating room. Some societal guidelines recommend the use of airborne precautions during aerosol-generating procedures on asymptomatic patients during the coronavirus disease pandemic, although evidence supporting this practice is limited. CONCLUSION: Viral transmission from patients exhibiting no symptoms in the operating room is plausible and efforts to reduce risk to healthcare providers include reducing aerosolization and wearing appropriate personal protective equipment, the feasibility of which will vary based on geographic risk and equipment availability.


RéSUMé: OBJECTIF: Le risque encouru par les travailleurs de la santé traitant des patients asymptomatiques infectés par le syndrome respiratoire aigu sévère du coronavirus 2 (SARS-CoV-2) en salle d'opération dépend de plusieurs facteurs. Ce compte rendu examine les données probantes concernant la présence asymptomatique ou pré-symptomatique du SARS-CoV-2, le risque de transmission des patients asymptomatiques, et les risques spécifiques associés aux interventions générant des aérosols. Nous passons également en revue différentes mesures de protection, telles que la minimisation des aérosols et l'utilisation d'équipements de protection individuelle, dans un contexte de traitement de patients asymptomatiques. SOURCE: Nous avons examiné la littérature publiée ainsi que les directives sociétales. CONSTATATIONS PRINCIPALES: Selon certaines données probantes, une proportion des personnes infectées par le SARS-CoV-2 possèdent des charges virales détectables avant la présence de symptômes, voire même sans manifestation de symptômes. Le degré de risque de transmission des patients asymptomatiques aux travailleurs de la santé dépendra de la prévalence de la maladie dans la population, une donnée difficile à évaluer sans dépistage généralisé. Les interventions générant des aérosols augmentent le risque de transmission virale des patients symptomatiques infectés aux travailleurs de la santé, mais la transmission de patients asymptomatiques n'a pas été rapportée. Les techniques visant à minimiser l'aérosolisation et les équipements de protection individuelle adaptés pourraient être utiles pour réduire le risque des travailleurs de la santé en salle d'opération. Certaines directives régionales et nationales recommandent le recours à des précautions contre la transmission par voie aérienne durant les interventions générant des aérosols pratiquées sur des patients asymptomatiques pendant la pandémie de coronavirus, bien que les données probantes appuyant cette pratique soient limitées. CONCLUSION: La transmission virale des patients asymptomatiques en salle d'opération est plausible et les efforts visant à réduire le risque pour les travailleurs de la santé comprennent la réduction de l'aérosolisation et le port d'équipements de protection individuelle adaptés, deux mesures dont la faisabilité variera en fonction du risque géographique et de la disponibilité des équipements.


Subject(s)
Asymptomatic Infections/epidemiology , Coronavirus Infections/transmission , Infectious Disease Transmission, Patient-to-Professional/prevention & control , Pneumonia, Viral/transmission , Aerosols , Betacoronavirus/isolation & purification , COVID-19 , Carrier State/epidemiology , Carrier State/virology , Coronavirus Infections/epidemiology , Health Personnel , Humans , Pandemics , Personal Protective Equipment , Pneumonia, Viral/epidemiology , SARS-CoV-2
20.
Travel Med Infect Dis ; 37: 101692, 2020.
Article in English | MEDLINE | ID: covidwho-1764004

ABSTRACT

Social distancing at its various levels has been a key measure to mitigate the transmission of COVID-19. The implementation of strict measures for social distancing is challenging, including in the Kingdom of Saudi Arabia (KSA) due to its level of urbanization, its social and religious norms and its annual hosting of high visibility international religious mass gatherings. KSA started introducing decisive social distancing measures early before the first case of COVID-19 was confirmed in the Kingdom. These ranged from suspension or cancelations of religious, entertainment and sporting mass gatherings and events such as the Umrah, temporary closure of educational establishments and mosques and postponing all non-essential gatherings, to imposing a curfew. These measures were taken in spite of their socio-economic, political and religious challenges in the interest of public and global health. The effect of these actions on the epidemic curve of the Kingdom and on the global fight against COVID-19 remains to be seen. However, given the current COVID-19 situation, further bold and probably unpopular measures are likely to be introduced in the future.


Subject(s)
Coronavirus Infections/prevention & control , Pandemics/prevention & control , Pneumonia, Viral/prevention & control , Betacoronavirus , COVID-19 , Crowding , Humans , Islam , SARS-CoV-2 , Saudi Arabia , Social Isolation , Travel
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