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1.
Journal of Patientreported Outcomes ; 6(1):123, 2022.
Artigo em Inglês | MEDLINE | ID: covidwho-2153720

RESUMO

BACKGROUND: Although there is extensive literature on the clinical benefits of COVID-19 vaccination, data on humanistic effects are limited. This study evaluated the impact of SARS-CoV-2 infection on symptoms, Health-Related Quality of Life (HRQoL) and Work Productivity and Impairment (WPAI) prior to and one month following infection between individuals vaccinated with BNT162b2 and those unvaccinated.

2.
European psychiatry : the journal of the Association of European Psychiatrists ; 64(Suppl 1):S253-S253, 2021.
Artigo em Inglês | EuropePMC | ID: covidwho-2072723

RESUMO

Introduction The paper will describe the experience as consultation-liaison psychiatrist during the Covid 19 Pandemic in a private hospital in Madrid, what we have learned and its implications given the considerable and increasing interest in European Consultation-Liaison research. Objectives Following the request of one of the internal medicine department doctors the service was initially provided for patients admitted with the infection but very quickly included relatives and also the hospital staff. Methods Patients were offered a telephone consultation that in most cases took place on a daily basis. Referrals where made by a doctor, some of them were locums due to the increasing demands of the service since patients from public hospitals were also admitted. Relatives were also referred by doctors and the frequency was more varied, depending on their needs. Members of the multidisciplinary team referred themselves.. Results Patients and their families felt that the telephone consultation was useful to them. The work with some members of the staff is ongoing and will continue given the toxic levels of stress that they had to face and the changes taking place at the institution at the time. Conclusions The COVID-19 pandemic and the short and long term consequences that will follow will increase our understanding the breadth and depth of Consultation-Liaison Psychiatry and the broad perspective required for a comprehensive evaluation and treatment of patients. My experience as psychoanalytic psychotherapist and organizational consultant proved most helpful.

3.
Revista Cubana de Pediatria ; 93, 2021.
Artigo em Espanhol | Scopus | ID: covidwho-2044863

RESUMO

Introduction: The COVID-19 disease caused by SARS-CoV-2 became a pandemic as of March 2020. Among the clinical manifestations of the peripheral nervous system may appear anosmia and ageusia. Objective: Demonstrate the importance of clinical and epidemiological diagnosis in the certainty criterion of COVID-19. Case presentation: 17-year-old male adolescent with loss of smell and family history of COVID-19, so he was left alone at home due to the admission in hospital of his family;he had two negative polymerase chain reaction tests in the first instance, without clinical picture of the apparent disease, until approximately 10 days after the appearance of the symptoms of the family, which begins with total loss of smell;the same test is repeated, which is negative again and he is referred to consultation for the study of anosmia. He was attended in Pediatrics service, a complete study is indicated and the interconsultation with the specialist of otolaryngology is carried out. All the complementary laboratory, microbiology and imaging tests were negative, so it was decided, due to the suspicion of COVID-19 and the family history, to perform serology for antibodies against SARS-CoV-2, which resulted in positive IgG. Conclusion: The retrospective clinical and epidemiological diagnosis allowed the certainty criterion of COVID-19 disease. © 2021, Editorial Ciencias Medicas. All rights reserved.

4.
IISE Annual Conference and Expo 2022 ; 2022.
Artigo em Inglês | Scopus | ID: covidwho-2012349

RESUMO

Given the high spread of Covid-19, many hospitals suffered from a shortage of ventilators to treat patients. Consequently, emergency resuscitators (ER) became popular as a cheaper and easier to manufacture option that would satisfy the need for ventilators in hospitals. These devices are characterized by an automated mechanism that tightens a Bag valve mask (BVM), commonly known as a manual resuscitator. The ERs main components are the controller, sensors, the Human Machine Interface (HMI), and the motor. For the effective design of these devices, the team must understand the relationship between components. In the iterative process of designing, changing one part can easily affect the operation of other components. This is the most critical points of the case study presented since it is not feasible to replace a component without considering the requirements of the other parts that make up the final product. Using a resuscitator developed by a Puerto Rican company as an example, if changes were to be made, to keep the current sensors, a Programmable Logic Controller (PLC) should be used as a controller. Changing the PLC affects the sensors and limits the options of the HMIs since many of them are designed to work with the same brand. On the other hand, when selecting the motor, the communication method and compatibility with the controller must be considered. For these reasons, this paper presents a case study to share the compatibility issues that are faced when developing this type of device. © 2022 IISE Annual Conference and Expo 2022. All rights reserved.

5.
Female Pelvic Medicine and Reconstructive Surgery ; 28(6):S33-S34, 2022.
Artigo em Inglês | EMBASE | ID: covidwho-2008694

RESUMO

Introduction: Postmenopausal women with recurrent urinary tract infections (RUTI) are repeatedly exposed to antibiotics and therefore at risk for colonization by multi-drug resistant organisms. Methenamine hippurate (MH) is FDAapproved for the prevention of RUTI;however, the mechanism of action of MH or, more specifically, the role of MH in the alteration of the urobiome is not known. Since preliminary data has shown that MH may be effective against some bacteria (e.g., Escherichia coli), but not others (e.g., Enterococcus faecalis), we hypothesize that resident bladder microbiota will be altered by administration of MH. Objective: Our objective is to determine the longitudinal effect of MH on the urobiome of postmenopausal women with RUTI. Methods: A longitudinal study with a convenient sample of 10 postmenopausal women with a clinical history of RUTI was conducted (Figure 1). UDI6 questionnaires, voided urine, catheterized urine, and peri-urethral swabs were obtained at baseline and three months after daily MH use. Expanded quantitative urine culture (EQUC) was performed on these specimens. In addition, during the 3-month timeframe, four self-collection windows were completed (windows A-D): (A) prior to initiating MH (baseline urobiome), (B) one week after starting MH, (C) two weeks before the 3-month follow-up, and (D) one week before the 3-month follow-up. Voided urine and peri-urethral swabs were collected daily for one week during windows A-D to determine how the urobiome changed. Sequencing of samples from these collection windows is pending. Results: Ten participants enrolled;however, three participants were not able to complete the study due to allergic reaction, improper handling of samples, and COVID infection. Six participants have completed the study;microbiological studies for one participant are still in process. There were no episodes of acute cystitis for any participant during the length of the study. UDI6 results suggested a trend towards a decrease in frequency, leakage with urgency, and abdominal pain;however, none of these were statistically significant (Table 1). Of the six remaining participants, the average baseline urine pH was 5.8 ± 0.8. For the completed participants, an initial microbiological comparison of EQUC results at baseline and 3-month visits show differences in sample diversity. Specifically, the number of species detected (richness) in catheterized urine increased for all but one participant (Figures 2A and 2B) though there was little or no changes in overall diversity (Shannon Index, Figure 2B) or evenness (Pielou's Index, Figure 2C) for any sample type. Exposure to MH did not result in the loss of uropathogenic species present in catheterized urine at baseline;instead, additional uropathogenic and commensal microbiota were detected at the 3-month visit. Conclusions: UDI6 trended towards symptom improvement in frequency, urge incontinence, and pain, consistent with RUTI prevention and symptoms control. Microbiological results suggest that MH increases the richness of the bladder urobiome. This consistent trend suggests MH may reduce RUTI events by altering the urobiome community richness instead of eliminating uropathogenic microbiota from the bladder. Further studies are needed to understand the interaction between MH and a host that is susceptible to uropathogen overgrowth (Table Presented).

6.
American Journal of Kidney Diseases ; 79(4):S91, 2022.
Artigo em Inglês | EMBASE | ID: covidwho-1996900

RESUMO

The COVID-19 pandemic limited health care access for individuals with multiple chronic medical conditions. Our aim was to evaluate the impact of COVID-19 on mental health and quality of health care in patients with chronic comorbidities such as DM, HTN and CKD. An online survey was sent to patients over the age of 18 years who have been seen at Joslin during the last 24 months. Surveys were sent to participants by Redcap or conducted through telephone. The survey consisted of 92 items that included COVID diagnosis, General Health, Home self-care, Vaccines, Exposure to COVID, Health- care access and delivery, Perceptions of healthcare quality during the COVID-19 Pandemic, Pregnancy, Mental well-being, Diet and lifestyle, and demographics. Anxiety and depression symptoms were assessed using the Patient Health Questionnaire-4 (PHQ-4). As of November 1, 2021, 1189 had completed the survey. The mean age of participants was 54.2 ± 17.3 years. Half were women, and 89.2% were White. One hundred-six reported to have had COVID-19 infection;94% had diabetes, 36% had HTN, and 8% had CKD. An income of < $50,000 was reported in 9% and 39% were college graduates. While half of the CKD participants felt COVID-19 made their quality of healthcare “worse or a lot worse”, 81% of the participants with CKD felt that their doctors were available to meet their healthcare needs. In addition, the majority of the CKD participants reported to have access to all of their medications during the pandemic. About 48% reported COVID-19 outbreak has negatively affected their mental health with 21% and 11% screened positive for anxiety and depression respectively. Results were similar in patients with CKD. Individuals with depression and anxiety were, more likely to be women and obese. Fifteen percent of the participants with depression and 10.6% with anxiety responded that COVID-19 made the quality of healthcare a lot worse compared to 3.6% in individuals with no depression and 3.3% with no anxiety respectively (p<0.001). The COVID-19 pandemic has made an impact on mental health and quality of healthcare in individuals with CKD.

7.
Gaceta Medica de Caracas ; 130:S450-S458, 2022.
Artigo em Espanhol | Scopus | ID: covidwho-1995012

RESUMO

Objectives: Determining Anti-COVID-19 vaccination range in a group of Venezuelan obstetrician-gynecologists, specifying the type of vaccine received, according to the vaccination schedule, symptomatology, and level of pathology: mild, moderate, or severe. M ethod: Descriptive and cross-sectional study in 173 Venezuelan obstetrician-gynecologists, members of WhatsApp group. The information was collected by WhatsApp, through a survey consisting of five questions: did you receive a COVID-19 vaccine? If you received it, what type of vaccine did you get? Please indicate dose dates. Have you been diagnosticated with COVID-19? If you had the disease, on what date did you make the diagnosis? were you treated at home? Did you require hospitalization or warrant ICU? Results: The majority of respondents were vaccinated (82.08 %);one group has not done so (9.82 %) and another has yet to complete its vaccination schedule (8.09 %). Seven types of vaccines were applied: Sinopharm - Vero Cell (69.71 %), Sputnik V (20.42 %), Pfizer (4.92 %), Johnson and Johnson (2.11 %), Moderna (1.40 %), Sinovac (0.70 %) and one respondent received a mixed vaccination schedule: AstraZeneca in its first dose and Pfizer in the second (0.70 %). 30.05 % of respondents admitted to having suffered from COVID-19, there were two reinfections (3.86 %). One of them, three months after receiving the second dose of Sputnik V, the other reinfection was in an unvaccinated respondent. Forty-one of the fifty-four cases occurred in unvaccinated people (75.92 %), eight were post-vaccinated (15.81 %) between three and twelve weeks after the second dose, and five with incomplete vaccination schedules (9.25 %). There were eight severe cases (14.81 %), four unvaccinated (50 %), three with an incomplete vaccination schedule (37.5 %), and one post-vaccinated (12.5 %), infected three weeks after completing their vaccination schedule with Simopharm - Vero Cell. Three obstetrician-gynecologist doctors died (5.55 % lethality), and none completed their respective vaccination schedules. Conclusions: Doctors and the entire health team are at high risk of contagion when caring for patients. Vaccination coverage of this personnel must be total. © 2022 Academia Nacional de Medicina. All rights reserved.

8.
Gaceta Medica de Caracas ; 130(2):304-316, 2022.
Artigo em Espanhol | Scopus | ID: covidwho-1989122

RESUMO

Objective: This work aims to provide a valid procedure to characterize and classify positive mental health profiles of subjects in prolonged confinement by COVID-19. M ethod: Methodologically, the factors prosocial attitude, self-control, personal satisfaction, autonomy, problem-solving and self-actualization, and interpersonal relationships were adopted in 285 individuals aged 18 to 75 years;the literature related to positive mental health, the application of Artificial Neural Networks and Cluster Analysis were reviewed, which allowed structuring a systematic analysis procedure to characterize and classify positive mental health profiles. Results: A procedure was achieved that integrates a cluster analysis that identified behavioral patterns and characterized groups of positive mental health and an artificial neural network that classifies positive mental health profiles into two groups distinguishing stages of the well-being of individuals and the normalized importance of the factors analyzed was established. Conclusion: From the results, it can be concluded that the proposed procedure that integrates cluster analysis and artificial neural networks can be used as a characterization and classification tool in studies where there are multiple variables, which complements traditional studies, providing robustness in the analysis. © 2022 Academia Nacional de Medicina. All rights reserved.

10.
FEBS Open Bio ; 12:261, 2022.
Artigo em Inglês | EMBASE | ID: covidwho-1976633

RESUMO

While the new coronavirus has turned our lives upside down causing millions of deaths, the historically known tuberculosis (TB) disease caused by Mycobacterium tuberculosis (MTB) was responsible for the loss of approximately 1.5 million lives alone in 2021. New anti- TB drugs are in an urgent need. A promising target is dUTPase, an enzyme preventing uracil incorporation into DNA. It is present in all multicellular species and in most microbes. Abolition of its activity potentially leads to DNA double strand breaks and cell death. Therefore, species-specific inhibition of MTB dUTPase may be a successful way of TB disease treatment. Currently no species-specific dUTPase inhibitor exists, but an interaction partner, protein Stl shows significantly different ability to inhibit dUTPase homologues from various species. We use Stl as a model to understand how species- specific differences in dUTPase structure may be harnessed in future inhibitor development. A remarkable species-specific characteristic of MTB dUTPase is a small surface sequence loop playing no direct role in enzyme activity but being essential for mycobacterial survival in a yet unknown way. What is the exact structural background of MTB dUTPase-Stl interaction? For this reason, we have crystallized a complex of MTB dUTPase and a truncated Stl protein mutant. And how the loop sequence may affect the MTB dUTPase protein structure on its own? For this answer, we obtained another X-ray diffraction dataset of a loop-lacking mutant of MTB dUTPase with 1.3 Å resolution. Surprisingly, electron density of the flexible C-terminal “arm” segment of the mutant dUTPase was missing from our dataset, contrary to the already crystallized wildtypeMTB dUTPase structures. We postulate that the loop sequence may restrict conformational flexibility of the dUTPase “arm”, making it more inhibitable by Stl compared to the loop-lacking mutant, as we know from our comparative steady-state enzyme activity inhibition measurements.

11.
Open Forum Infect Dis ; 9(6): ofac239, 2022 Jun.
Artigo em Inglês | MEDLINE | ID: covidwho-1922314

RESUMO

Background: Several observational studies demonstrated the passage of postvaccine antibodies through breast milk in women vaccinated against coronavirus disease 2019 (COVID-19), mostly with messenger RNA (mRNA)-based vaccines, but lacked long-term data. Methods: A 6-month prospective cohort study was performed to determine severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccine-induced antibody levels in the breast milk of 33 lactating healthcare workers at different timepoints after mRNA BNT162b2 Pfizer-BioNTech COVID-19 vaccination. Moreover, we examined the correlation of SARS-CoV-2 antibody levels between serum and breast milk, adverse events related to vaccination, and rate of SARS-CoV-2 infections. Results: Mothers' median age was 38 (interquartile range [IQR], 36-39) years and 15 (IQR, 10-22) months for infants. Median (IQR) SARS-CoV-2 immunoglobulin G (IgG) spike protein subunit S1 (S1) vaccine-induced levels at different timepoints for serum-milk pairs were 519 (234-937) to 1 (0-2.9) arbitrary units (AU)/mL at 2 weeks after first dose and 18 644 (9923-29 264) to 78 (33.7-128), 12 478 (6870-20 801) to 50.4 (24.3-104), 4094 (2413-8480) to 19.9 (10.8-51.9), 1350 (831-2298) to 8.9 (7.8-31.5) AU/mL at 2, 4, 12 and 24 weeks after second dose, respectively. We observed a positive correlation of antibody levels between serum and breast milk, no serious adverse events related to vaccination, and 2 (6%) COVID-19 vaccine breakthrough infections. Conclusions: Women vaccinated with Pfizer-BioNTech transmit antibodies into breast milk with a positive correlation with serum levels. Both decreased over time in a 6-month follow-up.

12.
BITACORA URBANO TERRITORIAL ; 32(2):227-240, 2022.
Artigo em Espanhol | Web of Science | ID: covidwho-1912294

RESUMO

This article seeks to understand the relationship between the production of urban space and the conditions of habitability in the self-produced neighborhoods of Metropolitan Lima in 2020, during the COVID-19 pandemic. As a case study, we chose the district of San Juan de Lurigancho (SJL) and developed the research under a mixed methodological approach. First, we characterized the living conditions in the self-produced neighborhoods of two communes of the district in order to see their relationship with COVID-19 infection. Finally, qualitative tools were used to delve deeper into the habitability conditions based on the narratives of the leaders in self-produced neighborhoods. Among the findings, diverse habitability conditions were found in the neighborhoods of the studied communes, where the impact of the pandemic did not represent a direct relationship with the contagion. In addition, the agency of local actors in the process of self-production of urban space is highlighted, as well as to other dimensions such as food security and health.

13.
American Journal of Respiratory and Critical Care Medicine ; 205:1, 2022.
Artigo em Inglês | English Web of Science | ID: covidwho-1880358
14.
Open forum infectious diseases ; 2022.
Artigo em Inglês | EuropePMC | ID: covidwho-1863899

RESUMO

Background Transfer of passive and active immunity through human milk is a key aspect in infant protection against infections. Several observational studies demonstrated the passage of postvaccine antibodies through breast milk in women vaccinated against COVID-19, mostly with mRNA-based vaccines, but lacked long-term data. Methods A six-month prospective cohort study was performed to determine SARS-CoV-2 vaccine-induced antibody levels in the breast milk of 33 lactating healthcare workers at different time-points after mRNA BNT162b2 Pfizer-BioNTech COVID-19 vaccination. Moreover, we examined the correlation of SARS-CoV-2 antibody levels between serum and breast milk, adverse events related to vaccination (AErV) and rate of SARS-CoV-2 infections. Results Mothers’ median (IQR) age was 38(36-39) years and 15(10-22) months for infants. SARS-CoV-2 IgG-S1 vaccine-induced levels at different time-points for serum–milk pairs, median (IQR), were: 519(234-937) to 1(0-2.9) arbitrary units (AU)/mL at 2w after first dose, 18,644(9,923-29,264) to 78(33.7-128) AU/mL at 2w, 12,478(6,870-20,801) to 50.4(24.3-104) AU/mL at 4w, 4,094(2,413-8,480) to 19.9(10.8-51.9) AU/mL at 12w, and 1,350(831-2,298) to 8.9(7.8-31.5) at 24w after second dose. We observed a positive correlation of antibody levels between serum and breast milk (Pearson correlation coefficient 0.68), no serious AErV and 2(6%) COVID-19 vaccine breakthrough infections. Conclusions Women vaccinated with Pfizer-BioNTech transmit antibodies into breast milk with a positive correlation with serum levels. Both decreased over time in a 6-month follow-up. Finally, Infants of breastfeeding vaccinated women could be acquiring vaccine antibodies for at least six months after vaccination and serum determination of SARS-CoV-2 IgG-S1 could indicate breastmilk antibody levels.

16.
Psicoperspectivas ; 20(3), 2021.
Artigo em Espanhol | Scopus | ID: covidwho-1847530

RESUMO

The COVID-19 pandemic has had catastrophic consequences worldwide in different scopes, such as healthcare, education, housing, among others. As an important consequence, it revealed the fragility of social protection systems in Latin America, as depicted in the lack of alternative mechanisms to respond to the complex demands raised by the pandemics. As for healthcare systems, all efforts were focused in COVID-19 patients, leaving aside other patients, as bedridden patients who used to receive complementary attention at home, causing a big deal of stress to their informal home care providers. This research analyzes the perceptions, challenges, and expectations of informal care providers in this pandemic context. Throughout a six-month period, 12 semi structured interviews were performed online. The information was analyzed based on the principles of Grounded Theory, showing this has been a period particularly negative for informal care providers, as the offer of support public services has been diminished, increasing the perception of abandonment and vulnerability. Public policies to be developed are also discussed. © 2021 Pontificia Universidad Catolica de Valparaiso. All rights reserved.

17.
Revista Cubana de Educacion Medica Superior ; 35, 2021.
Artigo em Espanhol | Scopus | ID: covidwho-1823844

RESUMO

Introduction: Every day, learning by doing becomes more necessary for the dental medicine student. The new circumstances imposed by COVID-19 is demonstrative of this as a fact. Objective: To analyze how learning by doing is implemented in the teaching-learning process, which contributes to the training of dental health professionals within higher medical education in Cuba. Methods: A bibliographic review was carried out through the Academic Google search engine and in various bibliographic databases, such as PubMed and SciELO. The descriptors selected initially were educación en el trabajo en estomatología [dental education at work], proceso de enseñanza-aprendizaje [teaching-learning process], didáctica de la educación superior [didactics of higher education], and educación médica superior [higher medical education], as well as their English equivalences. Seventy-nine sources were consulted, but, after they were filtered, 41 were selected, of which 75% correspond to publications made from 2015 to date. Results: The genesis of education at work within Cuban higher medical education is analyzed, together with the way it has developed until the impact of COVID-19. The topic is also reviewed according to the international context, where there is a growing concern about the search for more or more alternatives less equivalent in the training of these professionals. Conclusions: Learning by doing in the teaching-learning process that contributes to the training of dental health professionals in Cuba has been implemented mainly through education at work. Its application is linked to compliance with all the principles of didactics and an adequate contextualization of the various components of this process, which is essential in the new conditions that COVID-19 has imposed on medical education. © 2021, Editorial Ciencias Medicas. All rights reserved.

18.
11th International Conference on the Internet of Things, IoT 2021 ; : 223-227, 2021.
Artigo em Inglês | Scopus | ID: covidwho-1784892

RESUMO

Covid19 has heightened physical and mental challenges for people with Autism Spectrum Disorder (ASD). One of the main difficulties that parents of children with ASD faced during the pandemic was to plan and structure a daily routine for their kids. The disruption of the routine, together with the difficulty of combining work and the care of children has resulted in behavioral problems and stress, and anxiety for children and their parents. For these reasons, the main goal of this work was to develop an adaptive robot that helps children with autism to plan and self-manage their day, allowing children to become more independent. While most interactive tools for children with ASD are meant for professional use in therapy, Pepe robot is developed as a support tool for these children to use along the way, with adaptability, agencies, senses, and playfulness at the core of the design. By collecting information from the performance of the kid, it is able to adapt its behavior to the child's (and parent's) needs and desires, and therefore progress with the child. Building upon the principles of Positive Behavioral Support, emotional crises are prevented by embracing a long-run negotiation process, by which the child gets gradually closer to the end goal of self-autonomy. Intended to be adapted to the accentuated needs of these children, the robot combines traditional and computational elements to make the most out of the experience. This project included in-depth user research together with parents and experts, an interdisciplinary design approach, and a prototyping phase in which a prototype was tested with children with ASD. © 2021 Owner/Author.

19.
Angiologia ; 74(2):78-81, 2022.
Artigo em Espanhol | Web of Science | ID: covidwho-1772017

RESUMO

Introduction: COVID-19 infection has been associated with significant coagulation disorders, particularly hyperco-agulable states. We present two cases of aortic thrombosis associated with COVID-19 infection and their outcome. Case report: case 1. Patient with asymptomatic aortic arch thrombosis. Case 2. Patient with aortoiliac thrombosis with acute lower extremity ischemia. Discussion: up to 20 %of patients with COVID-19 have some complication, including bleeding disorders. Surgical treatment of patients with COVID-19 infection and arterial complications poses a complex scenario when deciding on therapeutic conduct.

20.
Biochimica Clinica ; 45(SUPPL 2):S84, 2022.
Artigo em Inglês | EMBASE | ID: covidwho-1733148

RESUMO

Introduction: In December 2019 a new pathology emerged in the region of Hubei, China. It is provoked by a virus that was later named 2019-nCov, and then renamed as SARSCoV-2.Considering previous studies and publications, we decided to evaluate biomarkers to determinate if and how they could be a useful tool to predict complications and lethality. Goals: we used the clinical data of 147 patients, whom we made a retrospective analysis of. We created two groups: survival and non survivals. We also divided them into two further classes: complications and non complications. We considered the following parameters: age, lymphocyte, neutrophil, platelet, Neutrohpile-tolymphocyte ratio (NLR), platelets-to-lymphocyte ratio (PLR), CRP and procalcitonine. The Majority of these markers were collected at the emergency room. Materials and methods: We built a database from 146 Patients that were randomly included, using as criteria of inclusion PCR test positive and admission at the ER, followed by hospitalization. All the data comes from the analytics at the moment of the admission for the big part of them, or, when incompletes, in the next 48/72 hour. We considered as complications the following ones: Trombosis, septic shock, superinfection, acute renal failure and hyponatremia. We collected the data from our Hospital Database, then we performed all the statistical analysis using the IBM SPSS software, version 25. All the findings were considered statistically significative if P value <0.05. Results: All the patients were included in the study. Among them, 44 were female patiens, 103 were male. We performed Kolgomoroff-Smirnoff test of normality, with the following results: All the parameters showed an asymmetric distribution but CRP. T student and Mann-Whitney tests were performed. Our result showed that the differences in Age, CRP and procalcitonine were significative as p<0,05 between the groups of survaivals and non survivals, while all the rest of parameters showed a non significative result. Conlcusion: Our results showed a significative difference for the parameters of Age, procalcitonine and CRP when it comes to survival and no survival group. This findigs suggest and somehow confirm the importance of this biomarkers in the evaluation of Covid-19 patients.

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