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1.
ClinicalTrials.gov; 18/03/2022; TrialID: NCT05298800
Clinical Trial Register | ICTRP | ID: ictrp-NCT05298800

RESUMO

Condition:

Safety;Immunogenicity, Vaccine;COVID-19 Vaccines;Influenza Vaccines;Pneumococcal Vaccines

Intervention:

Biological: Vaccine

Primary outcome:

Seroconversion rate of neutralizing antibody

Criteria:


Inclusion Criteria:

- Healthy adults 18 years old and older

- Over 6 months after primary immunization with COVID-19 vaccines

- Can understand and sign the consent

- Can provide effective personal identification

Exclusion Criteria:

- Has a history of COVID-19 infection

- Less than 6 months after primary immunization with COVID-19 vaccines

- Already vaccinated with influenza vaccines of that year

- Vaccinated with pneumococcal vaccines within 5 years

- Has a history of severe hypersensitivity reaction to vaccines

- Has uncontrolled seizure or other severe neural system illnesses

- Has a fever, chronic disease, or acute disease during immunization

- Gestation period, lactation period, or planning to get pregnant within 3 months

- Administrated with other drugs under research within 30 days before vaccination

- Received attenuated vaccines within 14 days before vaccination

- Received subunit vaccines or inactivated vaccines within 7 days before vaccination

- Other conditions based on researcher's judgement


2.
ClinicalTrials.gov; 19/10/2021; TrialID: NCT05087277
Clinical Trial Register | ICTRP | ID: ictrp-NCT05087277

RESUMO

Condition:

COVID-19

Primary outcome:

Neutralizing capabilities to variant COVID-19 after primary and booster vaccination;Titer of Subclass of IgG after primary and booster vaccination

Criteria:


Inclusion Criteria:

- Between the ages of 18 and 59

- Healthy

- No vaccination with COVID-19 before become participant

- Agreed to take a blood sample

Exclusion Criteria:

- who cannot take the COVID-19 vaccine due to some personal reasons

- history of SARS-CoV, SARS-CoV-2, or Middle East respiratory syndrome infection

- high-risk epidemiology history within 14 days before enrolment (eg, travel or
residence history in communities with case reports, or contact history with someone
infected with SARS-CoV-2)

- axillary temperature of more than 37·0?

- history of allergy to any vaccine component.


3.
ClinicalTrials.gov; 29/09/2021; TrialID: NCT05072496
Clinical Trial Register | ICTRP | ID: ictrp-NCT05072496

RESUMO

Condition:

COVID-19

Primary outcome:

Durability of humoral and cellular immune responses

Criteria:


Inclusion Criteria:

- Working at the CDC

- Between the ages of 18 and 59

- Healthy

- Not vaccinated with COVID-19 vaccine

- Agreed to take a blood sample

Exclusion Criteria:

- who cannot take the COVID-19 vaccine due to some personal reasons

- history of SARS-CoV, SARS-CoV-2, or Middle East respiratory syndrome infection

- high-risk epidemiology history within 14 days before enrolment (eg, travel or
residence history in communities with case reports, or contact history with someone
infected with SARS-CoV-2)

- axillary temperature of more than 37·0?

- history of allergy to any vaccine component.


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