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1.
Value in Health ; 26(6 Supplement):S258, 2023.
Artigo em Inglês | EMBASE | ID: covidwho-20245374

RESUMO

Objectives: Opioids play a significant role in the effective management of cancer-related pain. The COVID-19 lock down may have reduced access to opioids and caused a decline in the use of prescription of opioids among cancer survivors. This study compared opioid prescription rates among cancer survivors before and after the onset of COVID-19 pandemic using real-world electronic health records (EHR). Method(s): Cohort analyses of cancer patients using data from EHR database from the TriNetX, a global federated health research network across 76 healthcare organizations. We analyzed changes in prescription opioid use before (March 1, 2018, through March 1, 2019) and after onset of COVID-19 (April 01, 2020, through March 2021) among cancer survivors. The key outcome variable was any opioid prescription within 1 year of cancer diagnosis. One-to-one propensity score matching was used to balance the characteristics (age, sex, race, diagnoses including diabetes, hypertensive diseases, overweight, mood disorders, and visual disturbances) of the two cohorts. Data were analyzed using the TriNetX platform. Result(s): There were 1,502,143 cancer survivors before COVID-19 and 1,412,599 cancer survivors after the onset of COVID-19. The one-to-one propensity-score match yielded 1,382,561 cancer patients, mean age 64 at cancer diagnosis, and 73% were white. Percentage of opioid use among cancer patients declined from 35.6% before the COVID-19 to 35.1% after the onset of the pandemic (OR=0.976, 95% CI 0.971-0.981). Average number of opioid prescriptions within 1 year of cancer diagnosis declined from 5.7 before to 5.3 after the COVID-19 onset (p<0.001). Conclusion(s): Among cancer survivors, a small decline in prescription opioid use was observed after the onset of COVID-19 pandemic. Future studies are needed to distinguish the impact of revised guidelines, opioid prescription policy changes, and COVID-19 lock down on lower rates of prescription opioid use among cancer survivors.Copyright © 2023

2.
Value in Health ; 26(6 Supplement):S199, 2023.
Artigo em Inglês | EMBASE | ID: covidwho-20241120

RESUMO

Objectives: Many patients with long COVID experience at least one vision problem. This study determines the association of long COVID with seeing difficulties. Method(s): We conducted a cross-sectional analysis with the Census Household Pulse Survey data (N = 51,288). We excluded adults who reported contracting COVID within the past four weeks, those with missing data on seeing difficulty when infected with COVID, and long COVID. Long COVID was defined as having symptoms lasting three months or longer that the adults did not have prior to having COVID. Adults self-reporting to a question on seeing with "some difficulty," "a lot of difficulty," or "unable to do" were classified as having "seeing difficulties." We conducted Chi-square tests and logistic regressions with replicate weights. Logistic regressions adjusted for long COVID, sex, age, race and ethnicity, marital status, income, education, food sufficiency, health insurance, remote work, vaccine doses, region, depression, and anxiety. Result(s): During the survey period (November 2 - November 14, 2022), 37.3% reported seeing difficulties, and 14.4% reported long COVID. A higher percentage of adults with long COVID reported seeing difficulties than those without long COVID (47.6% vs. 31.9%). In the fully adjusted logistic regression model, compared to adults with no COVID or without long COVID, those with long COVID had greater odds of seeing difficulties (AOR = 1.50, 95%CI = 1.32, 1.70). We did not observe a statistically significant difference between adults without long COVID and no COVID (AOR = 1.01, 95%CI = 0.93, 1.10 p = 0.7888). Conclusion(s): One in eight adults had long COVID. Adults with long COVID had significantly higher odds of seeing difficulties than those without long COVID. Therefore, a follow-up of patients with long COVID needs to include screening for seeing difficulties. More research is needed on the links between long Covid and vision care.Copyright © 2023

3.
Journal of Research in Marketing and Entrepreneurship ; 2023.
Artigo em Inglês | Scopus | ID: covidwho-2301586

RESUMO

Purpose: Resilient firms are more likely to survive crisis. This paper aims to investigate the resilient behavior displayed by small and medium enterprise (SME) owners in the pandemic context and the sequence of antecedents leading to resilient behavior. Design/methodology/approach: Seven SME owners, from different business sectors, were interviewed twice in 8 months, to assess their actions and underlying entrepreneurial resilience. A model was developed depicting the sequence of activities leading to entrepreneurial resiliency behavior. The study was conducted in the capital city of Odisha, an eastern Indian state. Findings: The results indicate that entrepreneurial resiliency is manifested in various forms where the SME owners engage in bricolage. Resiliency has an inevitable time dimension, where SME owners estimate the period for which adversity is likely to persist. They focus on alternative action to demonstrate resiliency. It was also learnt that revenue management during a crisis requires entrepreneurial marketing with innovativeness, opportunity seeking and value creation to improve resiliency. Research limitations/implications: This research is important for policymakers who can strengthen resiliency through the support and provision of adequate information to SME owners. Educators can use the model for discussion and pedagogy. Finally, SME owners can evaluate their response behaviors to a crisis and draw insights. Originality/value: The approach of the study was longitudinal and qualitative. This study contributes to the literature gap on resiliency in the context of emerging markets and SMEs. © 2023, Emerald Publishing Limited.

4.
Intelligent Internet of Things for Smart Healthcare Systems ; : 31-48, 2023.
Artigo em Inglês | Scopus | ID: covidwho-2261615

RESUMO

The Internet of things (IoT) is a system of interconnected devices and linked electronic devices which can collect, transmit, and manage data without human or computer intervention. The IoT is also potential technology that transforms everyday objects into dependable and effective intelligent things. It has impacted every element of life;however, its influence on healthcare has become particularly profound because of its slicing facet shift. It is now feasible to link innovative items over the internet and provide more digitally connected world ways for special applications. In published research on IoT in health care and the COVID-19 epidemic, the potential of this platform is examined. This literature-based research might also help specialists imagine related problems and combat the COVID-19 outbreak. This study report examines the human healthcare IoT (H2IoT) state, including existing services, architecture, topology, tools, services, and healthcare applications. In modern hospitals, "IoT” technology and internet-connected digital gadgets are commonplace. Clinicians have now abandoned paper and have become entirely or partly reliant on devices linked to wireless connections and tablets. © 2023 selection and editorial matter, Durgesh Srivastava, Neha Sharma, Deepak Sinwar, Jabar H. Yousif, and Hari Prabhat Gupta;individual chapters, the contributors.

5.
Indian Journal of Biochemistry & Biophysics ; 59(5):528-535, 2022.
Artigo em Inglês | Web of Science | ID: covidwho-1894159

RESUMO

IL-6 levels are significantly elevated in COVID-19 patients and are associated with poor clinical outcomes. Inhibiting IL-6 is thought to be a unique therapeutic strategy for the control of dysregulated host responses in SARS-CoV-2. The present study focuses on evaluating the research productivity of IL-6 level in SARS-CoV-2 infection using various bibliometric indicators and analysed 4510 research papers related to IL-6 levels in SARS-CoV-2 from the Scopus database and VOS Viewer tool applied for visualization. The results revealed that ascendant trends in the publications and USA, China and Italy have secured top three position in numbers of publications. Study observed that "Dagna L." received top prolific author rank. Article entitled "Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China" received maximum of 15364 total citations, whereas "Frontiers in Immunology" and "Journal of Medical Virology" secured in top two highly productive journals in the subject with extreme link strength. With regard to organisation, "Tongji Medical College-China" reported highly dynamic organization. "COVID-19", "SARS-CoV-2";"Interleukin" received maximum occurrences with high link strength. In view of global mounting public health issue of COVID-19, primarily due to increased viral transmissibility and associated cytokine storm, the present study will helpful for the medical professionals to know the research trends and also library authority for updating collection development policy in the specific subject domains.

6.
Environmental Challenges ; : 100477, 2022.
Artigo em Inglês | ScienceDirect | ID: covidwho-1670469

RESUMO

Atmospheric formaldehyde (HCHO) has significant adverse health effects at higher concentrations. It is an unstable and inflammable organic compound, and is an index for atmospheric pollution. Although the ambient HCHO is due to methane oxidation, the localised enhancement in HCHO is mostly from the emissions of non-methane volatile organic compounds (NMVOCs). Therefore, assessment of spatial and temporal changes in NMVOCs are key for monitoring air quality and climate change. Here, we analyse two decades of atmospheric HCHO measurements and investigate the HCHO sources in India using satellite observations in 1997–2020. The measurements show very high HCHO concentrations in the Indo-Gangetic Plain (IGP), and south and east India, about 8–12 × 1015 molec. cm−2. The northwest region shows moderate concentrations, but Kashmir and northern regions of northeast show very small values of about 1–2 × 1015 molec. cm−2. Our analyses reveal significant increase in HCHO over India in all seasons, with the highest trends during March–May, about 0.3–0.5 × 1015 molec. cm−2 yr−1;suggesting the spread of pollution even to rural regions. Many ports and mining areas exhibit high positive HCHO trends, which also show new source regions and transport pathways of pollution. Furthermore, the analyses for the COVID-19 lockdown period expose significant contributions from sources other than anthropogenic origin (e.g. biogenic and pyrogenic). Therefore, this study indicates the need of new policy interventions for controlling Volatile Organic Compound (VOC) pollution in rural and urban India, and at the international seaports of Indian Ocean.

7.
Biomedicine (India) ; 41(3):592-598, 2021.
Artigo em Inglês | Scopus | ID: covidwho-1539157

RESUMO

Introduction and Aim: Secondary antiphospholipid syndrome (APLS) and rise in antiphospholipid antibody (APLA) has been linked to the development of Disseminated Intravascular Coagulation in COVID-19. But still controversies exist regarding the increase in APLA in COVID-19. Hence, the present study aimed to estimate the levels of APLA in COVID patients and its relationship with the severity of the disease. Materials and Methods: 40 RT PCR positive COVID-19 cases and normal control were recruited for the study. Biochemical and hematological findings were compared in both the groups. COVID-19 patients were further subdivided into survivor Vs non-survivor and based upon the CT findings of thorax they were grouped with vs without CT findings. Results: CRP, PCT, ESR were found to be significantly increased in COVID-19 patients. IgM & IgG APLA antibody (3.02±1.32 U/ml & 3.54±1.85 U/ml) were found to be within normal range in COVID cases. APLA did not show any correlation with serum ferritin, CRP, PCT, N/L ratio and MPV in COVID-19. No statistical difference was seen in the levels of APLA when compared in non-survivors vs survivors. Even APLA was within normal range in the patients who presented with pulmonary embolism (PE), venous thromboembolism (VTE) and succumbed to the disease. Serum ferritin and neutrophil to lymphocyte (N/L) ratio was found to be significantly higher in non-survivors. Conclusion: Hence, in our study APLA was within normal range and was not related to the severity of the disease. © 2021, Indian Association of Biomedical Scientists. All rights reserved.

8.
Journal of the American Academy of Child and Adolescent Psychiatry ; 60(10):S15, 2021.
Artigo em Inglês | EMBASE | ID: covidwho-1464741

RESUMO

Objectives: The pandemic prevented smooth running of the live groups in the child and adolescent partial hospitalization programs (PHPs), due to the social distancing guidelines. The need for mental health services for children was exacerbated due to limited peer interactions. Transitioning of the traditional partial programs to tele-PHP was a pressing need of the hour to maintain mental health services for children. This presentation highlights the various steps that were taken in the development of a successful tele-child PHP. Methods: First, the challenge was to adapt to a HIPAA-compliant virtual platform. After a trial, a HIPAA-compliant virtual platform was selected for telehealth delivery, and staff was appropriately trained. Individual email links were used to connect with patients for group therapy, individual and family therapy, and medication management. Initially, intakes were limited to inpatient unit discharges, and completed in-person and subsequent follow-up services were provided virtually. Eventually, all services were moved to virtual platforms, and community referrals were accepted. Staff was available on-site for in-person evaluation if needed. Next, electronic outcome measures were integrated to be completed by the parents/patients at home at intake and discharge. Meeting licensure requirements was important because physicians needed to be licensed in the state where the patient was. Results: Transitioning from traditional to tele-PHP was a challenging yet inspiring path. Tele-PHP was able to run smoothly within 1 to 2 weeks and was running virtual groups from March 2020 to July 2020, which moved to hybrid programming thereafter. It led to the increased access of mental health services for children including patients with social anxiety and autism spectrum disorder, who responded better to telehealth platforms, with improvement in participation and engagement in the program. Conclusions: Restrictions due to the pandemic led to the development of tele-PHP, despite various challenges and roadblocks. It helped us learn that telehealth services could be a potential long-term-care approach for the partial program and a reliable solution. Extensive research is needed to evaluate the effectiveness of the tele-PHP. DTT

9.
Medico-Legal Update ; 21(4):17-23, 2021.
Artigo em Inglês | EMBASE | ID: covidwho-1395829

RESUMO

The ongoing Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic has prevailed and continues to persist in the country and the world despite all preventive and regulatory measures taken by the government, health care and at an individual level. It does beg the question, why? It can be safely attributed to the fact that we are still learning about the epidemiological factors, the virological characteristics, clinical profile and the transmission dynamics of the disease. The situation is particularly challenging when we are coupling research to answer these questions while taking on board, precautionary measures to contain the tumultuous morbidities and mortality by rationing the scarce resources and manpower. The present study aims to provide an auxiliary insight into the epidemiological, topographic and weatherelements influencing COVID-19 from the 34 COVID-19 positive dead bodies sent for autopsy to Department of Forensic Medicine at Institute of Medical Sciences, Banaras Hindu University from 1 Feb 2020 to 31 March 2021. It also examines the counter productiveness for autopsy in certified cases of death with COVID-19 positive status in a common mortuary setup in India.

10.
Sustainable Cities and Society ; 74, 2021.
Artigo em Inglês | Scopus | ID: covidwho-1354029

RESUMO

The recent and projected upward trends in the frequency and intensity of climate-induced events in cities have enhanced the focus on adaptation. In addition to enhancing the capacity of cities to prepare for and absorb risks, adaptation measures provide multiple co-benefits. However, health co-benefits are among the least explored. These are now seen as increasingly important with the renewed focus on public health since the COVID-19 pandemic. This study reviews literature focused on the health co-benefits of urban climate change adaptation measures. Health co-benefits of seven different categories of adaptation measures are discussed. Results showed that existing evidence is mainly related to some categories such as critical infrastructure, nature-based solutions, and urban planning and design measures. Other adaptation categories like early warning systems;policy, management & governance, including local adaptation policies;and measures and strategies related to ‘knowledge, perceptions & behavior’ that mainly involve people's understanding and individual responses to climate change, are relatively underexplored. Moreover, it was discussed that some adaptation measures may result in health trade-offs and these needs to be further studied. Overall, through identifying health co-benefits, results of this review can make a strong case for further promotion of climate change adaptation in cities. © 2021

11.
Journal of Pediatric Endoscopic Surgery ; 3(2):65-72, 2021.
Artigo em Inglês | EMBASE | ID: covidwho-1269202

RESUMO

Introduction: The coronavirus disease 2019 (COVID-19) has mandated the pediatric urologists to adapt to the changing dynamics and adopt the strategy to minimise the collateral damage. The purpose of this study is to compile all the available literature and published guideline to facilitate the patient management. Materials and methods: PubMed, Scopus, and Google scholar database were systematically searched using the search terms “COVID-19” AND “pediatric” AND “urology”. All published papers retrieved from this search were considered for this review based on PRISMA guidelines. In addition to this, World Wide Web search was conducted for guidelines, and recommendations published by scientific societies and their websites were searched for the desired information. Results: Total eight articles and society recommendations met the inclusion criteria and included in the study. The general level of agreement was found on need to postpone the elective cases and ensuring the safety of hospital staff. The organ and life-threatening conditions like acute and symptomatic obstructive uropathy and testicular torsion should be treated on an emergent basis irrespective of COVID status. There is no evidence that any modality either open or laparoscopic has any advantage over the other. The protocols need to be modified based on stage of pandemic, availability of resources, and local guidelines. The restart of work once the pandemic is over should also be prioritised. Conclusion: There are very few articles and society guidelines on pediatric urology care in the COVID era, but all the available guidelines stress on prioritisation, protocol-based management, and improvisation as per the circumstances. Level of evidence: V.

12.
Journal of Indian Association for Child and Adolescent Mental Health ; 17(1):72-80, 2020.
Artigo em Inglês | EMBASE | ID: covidwho-1158656

RESUMO

Background: Students staying safe and comfortable at homes during this lockdown do have much impact on the anxiety levels. Aim: This study compares the anxiety levels of state in the first year medical students in two situations like few days prior to their scheduled internal examination and during the COVID 19 lockdown period. Methods: This prospective study involved consenting first year MBBS students. State version of State Trait Anxiety Inventory (STAI – S) was used to assess the level of anxiety through Google forms. The link to the form was given two times to the students in the state of anxiety;first time, a few days prior to the scheduled internal examination and then after 54 days of the COVID 19 pandemic lockdown. The cut-off score of 40 defines probable clinical levels of anxiety. Results: Response rates were 119 (79.3%) during the first time and 134 (89.3%) the second time. A total of 101 students (67.3%) responded to the STAI-S questionnaire in both situations. The mean anxiety scores were significantly lower in students before the internal examination than that of the COVID-19 lockdown period [(45.70±11.42) vs (47.97±10.80);p – 0.0394]. With cut off value of 40, 65 students were anxious before internal examination while 78 were anxious during the lockdown period. Conclusions: This study reveals students are a vulnerable group having high anxiety due to COVID – 19 lockdown, which may be due to future academic uncertainties, restricted movement and adjustment with family members. It is essential that students are assessed for anxiety, stress and depression at regular intervals, and active intervention is provided to them in such situations.

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